Rabbit anti-Human KHDRBS3 Polyclonal Antibody | anti-KHDRBS3 antibody

KHDRBS3 Antibody

Cat. Num. AAA7044136

• Gene Names: KHDRBS3; Etle; SALP; SLM2; SLM-2; TSTAR; T-STAR; etoile
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry
• Purity: Antigen Affinity Purified
• Synonyms: KHDRBS3; Polyclonal Antibody; KHDRBS3 Antibody; KH domain-containing; RNA-binding; signal transduction-associated protein 3; RNA-binding protein T-Star; Sam68-like mammalian protein 2; SLM-2; Sam68-like phosphotyrosine protein; SALP; SLM2; anti-KHDRBS3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 346

• Applicable Applications for anti-KHDRBS3 antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Application Notes: Recommended dilution: IHC: 1:20-1:200
• Species: Human
• Immunogen: Recombinant human KH domain-containing, RNA-binding, signal transduction-associated protein 3 protein (C-170AA)
• Conjugate: Non-conjugated
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-9474
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis tissue using MBS7044136 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7044136 at dilution 1:100)

Related Product Information for anti-KHDRBS3 antibody

RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro.

NCBI and Uniprot Product Information

• NCBI GI #: 5730073
• NCBI GeneID: 10656
• NCBI Accession #: NP_006549.1
• NCBI GenBank Nucleotide #: NM_006558.2
• UniProt Accession #: O75525; Q6NUL8; Q9UPA8
• Molecular Weight: 30,250 Da
• NCBI Official Full Name: KH domain-containing, RNA-binding, signal transduction-associated protein 3
• NCBI Official Synonym Full Names: KH RNA binding domain containing, signal transduction associated 3
• NCBI Official Symbol: KHDRBS3
• NCBI Official Synonym Symbols: Etle; SALP; SLM2; SLM-2; TSTAR; T-STAR; etoile
• NCBI Protein Information: KH domain-containing, RNA-binding, signal transduction-associated protein 3
• UniProt Protein Name: KH domain-containing, RNA-binding, signal transduction-associated protein 3
• Protein Family: KH domain-containing, RNA-binding, signal transduction-associated protein
• UniProt Gene Name: KHDRBS3
• UniProt Synonym Gene Names: SALP; SLM2; SLM-2
• UniProt Entry Name: KHDR3_HUMAN

Uniprot Description

KHDRBS3: RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA- binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. Belongs to the KHDRBS family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 8q24.2

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; RNA binding

Biological Process: spermatogenesis