Western Blot (WB)
(Western blot analysis of extracts from HeLa cells, using KCTD5 Antibody. The lane on the left was treated with blocking peptide.)
Rabbit KCTD5 Polyclonal Antibody | anti-KCTD5 antibody
KCTD5 Antibody
Reactivity
Human, Mouse, RatPredicted: Pig, Bovine, Sheep, Rabbit, Dog
Applications
Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
KCTD5; Polyclonal Antibody; KCTD5 Antibody; BTB/POZ domain-containing protein KCTD5; FLJ20040; KCTD5_HUMAN; Potassium channel tetramerisation domain containing 5; anti-KCTD5 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Predicted: Pig, Bovine, Sheep, Rabbit, Dog
Predicted: Pig, Bovine, Sheep, Rabbit, Dog
Clonality
Polyclonal
Isotype
IgG
Specificity
KCTD5 Antibody detects endogenous levels of KCTD5.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
234
Applicable Applications for anti-KCTD5 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide derived from human KCTD5.
Tissue Specificity
Up-regulated in peripheral blood lymphocytes stimulated through the T-cell receptor.
Fragment
Fab Fragment
Conjugate
Unconjugated
Subcellular Location
Nucleus; Cytosol
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of extracts from HeLa cells, using KCTD5 Antibody. The lane on the left was treated with blocking peptide.)
Western Blot (WB)
(Western blot analysis of extracts from HeLa cells, using KCTD5 Antibody. The lane on the left was treated with blocking peptide.)
Related Product Information for anti-KCTD5 antibody
Description: Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex. Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4.
Subunit Structure: Homopentamer. Interacts (via C-terminus) with GRASP55/GORASP2. Interacts with CUL3 and with ubiquitinated proteins. Interacts with adeno-associated virus 2 (AAV-2) REP proteins.
Similarity: The BTB (POZ) domain is atypical and mediates the formation of a homopentamer instead of a homotetramer. Homopentamerization is due to the presence of 4 residues in the BTB (POZ) domain: Leu-56, Gly-100, Val-112 and Ala-118.
Subunit Structure: Homopentamer. Interacts (via C-terminus) with GRASP55/GORASP2. Interacts with CUL3 and with ubiquitinated proteins. Interacts with adeno-associated virus 2 (AAV-2) REP proteins.
Similarity: The BTB (POZ) domain is atypical and mediates the formation of a homopentamer instead of a homotetramer. Homopentamerization is due to the presence of 4 residues in the BTB (POZ) domain: Leu-56, Gly-100, Val-112 and Ala-118.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 26 kDa
Predicted: 27 kDa
Predicted: 27 kDa
NCBI Official Full Name
BTB/POZ domain-containing protein KCTD5
NCBI Official Synonym Full Names
potassium channel tetramerization domain containing 5
NCBI Official Symbol
KCTD5
NCBI Protein Information
BTB/POZ domain-containing protein KCTD5
UniProt Protein Name
BTB/POZ domain-containing protein KCTD5
Protein Family
UniProt Gene Name
KCTD5
UniProt Entry Name
KCTD5_HUMAN
Uniprot Description
KCTD5: Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex. Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4.
Protein type: Channel, potassium
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: nucleus; cytosol
Molecular Function: protein binding; protein complex binding
Biological Process: viral reproduction; protein homooligomerization
Research Articles on KCTD5
Similar Products
Product Notes
The KCTD5 kctd5 (Catalog #AAA9611855) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KCTD5 Antibody reacts with Human, Mouse, Rat Predicted: Pig, Bovine, Sheep, Rabbit, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's KCTD5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the KCTD5 kctd5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCTD5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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