Western Blot (WB)
(KCNMB2 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the KCNMB2 antibody detected the KCNMB2 protein (arrow).)
Rabbit anti-Human KCNMB2 Polyclonal Antibody | anti-Kcnmb2 antibody
KCNMB2, NT (KCNMB2, Calcium-activated potassium channel subunit beta-2, BK channel subunit beta-2, Calcium-activated potassium channel, subfamily M subunit beta-2, Charybdotoxin receptor subunit beta-2, Hbeta3, K(VCA)beta-2, Maxi K channel subunit beta-2,
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Western Blot (WB)
(KCNMB2 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the KCNMB2 antibody detected the KCNMB2 protein (arrow).)
Western Blot (WB)
(KCNMB2 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the KCNMB2 antibody detected the KCNMB2 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
a Ca(2+)-activated K(+) (BK) channel responsible for the large K(+) conductance in inner hair cells [RGD, Feb 2006]
Uniprot Description
Function: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex
By similarity.
Subunit structure: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB2 per KCNMA1 tetramer
By similarity.
Subcellular location: Membrane; Multi-pass membrane protein
By similarity.
Tissue specificity: Highly expressed in brain and heart. Also expressed in lung. Ref.3
Domain: The ball and chain domain mediates the inactivation of KCNMA1. It occludes the conduction pathway of KCNMA1 channels, and comprises the pore-blocking ball domain (residues 1-17) and the chain domain (residues 20-45) linking it to the transmembrane segment. The ball domain is made up of a flexible N-terminus anchored at a well ordered loop-helix motif. The chain domain consists of a 4-turn helix with an unfolded linker at its C-terminus
By similarity.
Post-translational modification: N-glycosylated
By similarity.
Sequence similarities: Belongs to the KCNMB (TC 8.A.14.1) family. KCNMB2 subfamily. [View classification]
Research Articles on Kcnmb2
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Product Notes
The Kcnmb2 kcnmb2 (Catalog #AAA6012372) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KCNMB2, NT (KCNMB2, Calcium-activated potassium channel subunit beta-2, BK channel subunit beta-2, Calcium-activated potassium channel, subfamily M subunit beta-2, Charybdotoxin receptor subunit beta-2, Hbeta3, K(VCA)beta-2, Maxi K channel subunit beta-2, reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KCNMB2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the Kcnmb2 kcnmb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCNMB2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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