Rabbit anti-Human KATNA1 Polyclonal Antibody | anti-KATNA1 antibody

KATNA1, NT (KATNA1, Katanin p60 ATPase-containing subunit A1, p60 katanin) (APC)

Cat. Num. AAA6312116

• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: KATNA1; Polyclonal Antibody; NT (KATNA1; Katanin p60 ATPase-containing subunit A1; p60 katanin) (APC); p60 katanin; anti-KATNA1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-KATNA1 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: KATNA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic between 58-85 amino acids selected from the N-terminal region of human KATNA1.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(KATNA1 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the KATNA1 antibody detected the KATNA1 protein (arrow).)

Related Product Information for anti-KATNA1 antibody

Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA family of ATPases. [provided by RefSeq].

Product Categories/Family for anti-KATNA1 antibody

Antibodies; Enzymes; ATPase

References

Olson, J.E., et al. Breast Cancer Res. Treat. (2010). In press: Iwaya, N., et al. J. Biol. Chem. 285(22):16822-16829(2010). Sudo, H., et al. Hum. Mol. Genet. 17(16):2524-2540(2008). Mungall, A.J., et al. Nature 425(6960):805-811(2003). Buster, D., et al. J. Cell. Sci. 115 (PT 5), 1083-1092 (2002).

NCBI and Uniprot Product Information

• NCBI GI #: 5901990
• NCBI GeneID: 11104
• NCBI Accession #: NP_008975.1
• NCBI GenBank Nucleotide #: NM_007044.3
• UniProt Accession #: O75449; Q5TFA8; Q5TFA9; Q86VN2; Q9NU52; E1P5A3
• Molecular Weight: 35,319 Da
• NCBI Official Full Name: katanin p60 ATPase-containing subunit A1 isoform 1
• NCBI Official Synonym Full Names: katanin p60 (ATPase containing) subunit A 1
• NCBI Official Symbol: KATNA1
• NCBI Protein Information: katanin p60 ATPase-containing subunit A1; KATNA1; p60 katanin; katanin p60 subunit A1; katanin p60 (ATPase-containing) subunit A 1
• UniProt Protein Name: Katanin p60 ATPase-containing subunit A1
• UniProt Gene Name: KATNA1
• UniProt Entry Name: KTNA1_HUMAN

NCBI Description

Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA family of ATPases. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Feb 2011]