Western Blot (WB)
(Western Blot: Sample: Lane1: Mouse Brain Tissue; Lane2: Mouse Spleen Tissue; Lane3: Human Hela Cells.)
Rabbit anti-Mouse Katanin P60 Subunit A 1 Polyclonal Antibody | anti-KATNA1 antibody
Katanin P60 Subunit A 1 (KATNA1) Polyclonal Antibody
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Enzyme-linked Immunosorbent Assay: 1:100-200
Usage: 10uL per well when 3,3'-Diaminobenzidine(DAB) as the substrate.
5uL per well when used in enhanced chemilumescent (ECL).
Note: The quality control is specifically manufactured as the positive control.Not used for other purposes.
Loading Buffer: 100mM Tris(pH8.8), 2% SDS, 200mM NaCl, 50% glycerol,BPB 0.01%, NaN3 0.02%.
Western Blot (WB)
(Western Blot: Sample: Lane1: Mouse Brain Tissue; Lane2: Mouse Spleen Tissue; Lane3: Human Hela Cells.)
Western Blot (WB)
(Western Blot: Sample: Lane1: Mouse Brain Tissue; Lane2: Mouse Spleen Tissue; Lane3: Human Hela Cells.)
Western Blot (WB)
(Western Blot: Sample: Recombinant KATNA1, Mouse.)
Western Blot (WB)
(Western Blot: Sample: Recombinant KATNA1, Mouse.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Ovary Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Ovary Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Liver Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Liver Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Pancreas Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Pancreas Tissue)
NCBI and Uniprot Product Information
Uniprot Description
KATNA1: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays, such as during disassembly of interphase microtubules at the G2-M transition. May also be required for microtubule release from the centrosome after nucleation. In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons, microtubule release within the cell body may allow their subsequent transport into neuronal processes by microtubule dependent motor proteins. This transport is required for axonal growth. Belongs to the AAA ATPase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.6.4.3; Hydrolase; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 10|10 A1
Cellular Component: axon; cell soma; centrosome; cytoplasm; cytoskeleton; growth cone; lipid droplet; microtubule; midbody; nucleus; plasma membrane; spindle; spindle pole
Molecular Function: ATP binding; ATPase activity; hydrolase activity; microtubule binding; microtubule-severing ATPase activity; nucleotide binding; protein binding; protein heterodimerization activity
Biological Process: cell cycle; cell division; cytoplasmic microtubule organization; microtubule bundle formation; microtubule severing; neuron migration; protein localization
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Product Notes
The KATNA1 katna1 (Catalog #AAA2032349) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Katanin P60 Subunit A 1 (KATNA1) Polyclonal Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Katanin P60 Subunit A 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western Blot: 1:50-400 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the KATNA1 katna1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Katanin P60 Subunit A 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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