Rabbit anti-Human, Mouse KAT14 Polyclonal Antibody | anti-KAT14 antibody

KAT14 Rabbit pAb

Cat. Num. AAA4759196

• Gene Names: CSRP2BP; ATAC2; KAT14; CRP2BP; PRO1194; dJ717M23.1
• Reactivity: Human, Mouse
• Applications: Western Blot, Immunohistochemistry
• Purity: Affinity purified
• Synonyms: KAT14; Polyclonal Antibody; KAT14 Rabbit pAb; lysine acetyltransferase 14; ATAC2; CRP2BP; CSRP2BP; PRO1194; dJ717M23.1; anti-KAT14 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purified
• Form/Format: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: 0.6mg/ml (varies by lot)

• Applicable Applications for anti-KAT14 antibody: Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
• Application Notes: WB: 1:500-1:2000; IHC-P: 1:30-1:150
• Immunogen: Fusion protein of human KAT14
• Conjugation: Unconjugated
• Modification: Unmodified
• Preparation and Storage: Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western Blot analysis of KAT14 in Mouse brain tissue lysate using KAT14 Rabbit pAb at dilution 1/300)

Immunohistochemistry (IHC)

(Immunohistochemistry of KAT14 in paraffin-embedded Human ovarian cancer tissue using KAT14 Rabbit pAb at dilution 1/20. Predicted cell location: Nucleus)

Related Product Information for anti-KAT14 antibody

CSRP2 is a protein containing two LIM domains, which are double zinc finger motifs found in proteins of diverse function. CSRP2 and some related proteins are thought to act as protein adapters, bridging two or more proteins to form a larger protein complex. The protein encoded by this gene binds to one of the LIM domains of CSRP2 and contains an acetyltransferase domain. Although the encoded protein has been detected in the cytoplasm, it is predominantly a nuclear protein. Alternatively spliced transcript variants have been described.

NCBI and Uniprot Product Information

• NCBI GI #: 308153608
• NCBI GeneID: 57325
• UniProt Accession #: Q9H8E8; Q96GW6; Q96IH3; Q9HBF0; Q9UIY5; A2A2I5
• Molecular Weight: 74,324 Da
• NCBI Official Full Name: Cysteine-rich protein 2-binding protein
• NCBI Official Synonym Full Names: CSRP2 binding protein
• NCBI Official Symbol: CSRP2BP
• NCBI Official Synonym Symbols: ATAC2; KAT14; CRP2BP; PRO1194; dJ717M23.1
• NCBI Protein Information: cysteine-rich protein 2-binding protein
• UniProt Protein Name: Cysteine-rich protein 2-binding protein
• Protein Family: Cysteine-rich protein 2-binding protein
• UniProt Gene Name: CSRP2BP
• UniProt Synonym Gene Names: CSRP2-binding protein; ATAC2; CRP2BP
• UniProt Entry Name: CSR2B_HUMAN

NCBI Description

CSRP2 is a protein containing two LIM domains, which are double zinc finger motifs found in proteins of diverse function. CSRP2 and some related proteins are thought to act as protein adapters, bridging two or more proteins to form a larger protein complex. The protein encoded by this gene binds to one of the LIM domains of CSRP2 and contains an acetyltransferase domain. Although the encoded protein has been detected in the cytoplasm, it is predominantly a nuclear protein. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2011]

Uniprot Description

CSRP2BP: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 20p11.23

Cellular Component: cytoplasm; nucleus

Molecular Function: histone acetyltransferase activity; LIM domain binding; protein binding

Biological Process: establishment and/or maintenance of chromatin architecture; G2/M transition of mitotic cell cycle