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Western Blot (WB) (Western blot analysis of extracts from 293 cells and A549 cells, using BMP8B antibody.)

Rabbit anti-Human BMP8B Polyclonal Antibody | anti-BMP8B antibody

BMP8B Antibody

Gene Names
BMP8B; OP2; BMP8
Reactivity
Human
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
BMP8B; Polyclonal Antibody; BMP8B Antibody; Bone morphogenetic protein 8B; BMP-8B; BMP-8; BMP8; Osteogenic protein 2; anti-BMP8B antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total BMP8B protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
402
Applicable Applications for anti-BMP8B antibody
Western Blot (WB)
Application Notes
Western blotting: 1:500~1:3000
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from internal of human BMP8B.
Target Name
BMP8B
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts from 293 cells and A549 cells, using BMP8B antibody.)

Western Blot (WB) (Western blot analysis of extracts from 293 cells and A549 cells, using BMP8B antibody.)
Related Product Information for anti-BMP8B antibody
Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis By similarity.Oezkaynak E., J. Biol. Chem. 267:25220-25227(1992).Onishi M., Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.Gregory S.G., Nature 441:315-321(2006).
Product Categories/Family for anti-BMP8B antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
656
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39,151 Da
NCBI Official Full Name
bone morphogenetic protein 8B preproprotein
NCBI Official Synonym Full Names
bone morphogenetic protein 8b
NCBI Official Symbol
BMP8B
NCBI Official Synonym Symbols
OP2; BMP8
NCBI Protein Information
bone morphogenetic protein 8B
UniProt Protein Name
Bone morphogenetic protein 8B
UniProt Gene Name
BMP8B
UniProt Synonym Gene Names
BMP8; BMP-8; BMP-8B; OP-2
UniProt Entry Name
BMP8B_HUMAN

NCBI Description

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity. [provided by RefSeq, Jul 2008]

Uniprot Description

BMP8B: Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. Belongs to the TGF-beta family.

Protein type: Secreted, signal peptide; Secreted; Cytokine

Chromosomal Location of Human Ortholog: 1p35-p32

Cellular Component: extracellular space

Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: regulation of apoptosis; BMP signaling pathway; ossification; regulation of MAPKKK cascade; cartilage development; skeletal development; cell development; growth

Research Articles on BMP8B

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Product Notes

The BMP8B bmp8b (Catalog #AAA9408481) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BMP8B Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BMP8B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500~1:3000. Researchers should empirically determine the suitability of the BMP8B bmp8b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BMP8B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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