Western Blot (WB)
(WB Suggested Anti-KANK2 AntibodyTitration: 1.0 ug/mlPositive Control: Fetal Liver)
Rabbit KANK2 Polyclonal Antibody | anti-KANK2 antibody
KANK2 antibody - C-terminal region
Western Blot (WB)
(WB Suggested Anti-KANK2 AntibodyTitration: 1.0 ug/mlPositive Control: Fetal Liver)
Western Blot (WB)
(WB Suggested Anti-KANK2 AntibodyTitration: 1.0 ug/mlPositive Control: Fetal Liver)
Target Description: The function of this protein remains unknown.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair. [provided by RefSeq, Jul 2016]
Uniprot Description
ANKRD25: a mammalian growth regulatory protein containing five Ankyrin repeats, common protein-protein interaction motifs. Ankyrin repeats are found in proteins with diverse functions including transcriptional initiators, cell-cycle regulators, cytoskeletal, and ion transporters. Three alternatively spliced isoforms have been described.
Protein type: Transcription regulation
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: mitochondrion; cytoplasm
Molecular Function: protein binding
Biological Process: negative regulation of cell proliferation; transcription, DNA-dependent; apoptosis; negative regulation of programmed cell death; negative regulation of transcription from RNA polymerase II promoter; negative regulation of estrogen receptor signaling pathway
Disease: Palmoplantar Keratoderma And Woolly Hair
Research Articles on KANK2
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Product Notes
The KANK2 kank2 (Catalog #AAA3215683) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KANK2 antibody - C-terminal region reacts with Tested Reactivity: Human (Predicte Reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KANK2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the KANK2 kank2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: DSGVCKVDKQ NRAGYSPIML TALATLKTQD DIETVLQLFR LGNINAKASQ. It is sometimes possible for the material contained within the vial of "KANK2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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