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Western Blot (WB) (Western blot analysis of K2P4.1 on different lysates using anti-K2P4.1 antibody at 1/500 dilution. Positive control�� Lane1: Mouse colon Lane2: Rat kidney)

Rabbit anti-Human, Mouse K2P4.1 Polyclonal Antibody | anti-K2P4.1 antibody

K2P4.1 Antibody

Gene Names
KCNK4; TRAAK; K2p4.1; TRAAK1
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
Peptide affinity purified.
Synonyms
K2P4.1; Polyclonal Antibody; K2P4.1 Antibody; K2p4.1 antibody; K2P4.1 potassium channel antibody; KCNK 4 antibody; MGC144821 antibody; Potassium channel subfamily K member 4 antibody; Potassium inwardly rectifying channel subfamily K member 4 antibody; TRAAK antibody; TRAAK1 antibody; TRAAKt antibody; TWIK related arachidonic acid stimulated potassium channel protein antibody; Two pore K (+) channel KT4.1 antibody; Two pore K+ channel KT4.1 antibody; Two pore potassium channel KT4.1 antibody; anti-K2P4.1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Peptide affinity purified.
Form/Format
1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-K2P4.1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes
WB: 1:500
IHC: 1:50-1:200
FC/FACS: 1:50-1:100
Immunogen
Synthetic peptide within human K2P4.1 aa 320-380.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.

Western Blot (WB)

(Western blot analysis of K2P4.1 on different lysates using anti-K2P4.1 antibody at 1/500 dilution. Positive control�� Lane1: Mouse colon Lane2: Rat kidney)

Western Blot (WB) (Western blot analysis of K2P4.1 on different lysates using anti-K2P4.1 antibody at 1/500 dilution. Positive control�� Lane1: Mouse colon Lane2: Rat kidney)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded rat large intestine tissue using anti-K2P4.1 antibody. Counter stained with hematoxylin.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded rat large intestine tissue using anti-K2P4.1 antibody. Counter stained with hematoxylin.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-K2P4.1 antibody. Counter stained with hematoxylin.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-K2P4.1 antibody. Counter stained with hematoxylin.)

Flow Cytometry (FC/FACS)

(Flow cytometric analysis of HepG2 cells with K2P4.1 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.)

Flow Cytometry (FC/FACS) (Flow cytometric analysis of HepG2 cells with K2P4.1 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.)
Product Categories/Family for anti-K2P4.1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,704 Da
NCBI Official Full Name
potassium channel subfamily K member 4
NCBI Official Synonym Full Names
potassium channel, subfamily K, member 4
NCBI Official Symbol
KCNK4
NCBI Official Synonym Symbols
TRAAK; K2p4.1; TRAAK1
NCBI Protein Information
potassium channel subfamily K member 4; K2P4.1 potassium channel; two pore K+ channel KT4.1; two pore K(+) channel KT4.1; two pore potassium channel KT4.1; TWIK-related arachidonic acid-stimulated potassium channel protein
UniProt Protein Name
Potassium channel subfamily K member 4
UniProt Gene Name
KCNK4
UniProt Synonym Gene Names
TRAAK; TRAAK
UniProt Entry Name
KCNK4_HUMAN

NCBI Description

Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The encoded protein homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids. [provided by RefSeq, Jul 2008]

Uniprot Description

KCNK4: Voltage insensitive, instantaneous, outwardly rectifying potassium channel. Outward rectification is reversed at high external K(+) concentrations. Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: plasma membrane; integral to membrane

Molecular Function: potassium channel activity; voltage-gated ion channel activity

Biological Process: synaptic transmission; potassium ion transport

Research Articles on K2P4.1

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Product Notes

The K2P4.1 kcnk4 (Catalog #AAA9435403) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The K2P4.1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's K2P4.1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB: 1:500 IHC: 1:50-1:200 FC/FACS: 1:50-1:100. Researchers should empirically determine the suitability of the K2P4.1 kcnk4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "K2P4.1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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