Western Blot (WB)
((0.1ug/ml) staining of human liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat JIK/TAOK3 Polyclonal Antibody | anti-TAOK3 antibody
Goat anti-JIK/TAOK3 Antibody
Immunohistochemistry: In paraffin embedded Human Prostate shows staining of cytoplasm of secretory cells in the glands. Recommended concentration, 2-3ug/ml.
Western Blot: Approx 100kDa band observed in human Liver lysate (calculated MW of 105kDa according to NP_057365). Recommended concentration: 0.3-1. 0 ug/ml.
Western Blot (WB)
((0.1ug/ml) staining of human liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
((0.1ug/ml) staining of human liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Immunohistochemistry (IHC)
((2.5ug/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.)
Immunohistochemistry (IHC)
((2.5ug/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.)
NCBI and Uniprot Product Information
Uniprot Description
TAO3: Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress- activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF). Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Protein type: Protein kinase, STE; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; STE group; STE20 family; TAO subfamily
Chromosomal Location of Human Ortholog: 12q
Cellular Component: cytoplasm; plasma membrane
Molecular Function: ATP binding; protein binding; protein kinase inhibitor activity; protein serine/threonine kinase activity; receptor signaling protein serine/threonine kinase activity; transferase activity
Biological Process: DNA repair; MAPKKK cascade; mitotic cell cycle G2/M transition DNA damage checkpoint; negative regulation of JNK cascade; negative regulation of protein kinase activity; positive regulation of JNK activity; positive regulation of JNK cascade; positive regulation of stress-activated MAPK cascade; protein amino acid autophosphorylation; protein amino acid phosphorylation; response to DNA damage stimulus
Research Articles on TAOK3
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Product Notes
The TAOK3 taok3 (Catalog #AAA420825) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-JIK/TAOK3 Antibody reacts with Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow and may cross-react with other species as described in the data sheet. AAA Biotech's JIK/TAOK3 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Peptide ELISA: Antibody detection limit dilution 1: 32000. Immunohistochemistry: In paraffin embedded Human Prostate shows staining of cytoplasm of secretory cells in the glands. Recommended concentration, 2-3ug/ml. Western Blot: Approx 100kDa band observed in human Liver lysate (calculated MW of 105kDa according to NP_057365). Recommended concentration: 0.3-1. 0 ug/ml. Researchers should empirically determine the suitability of the TAOK3 taok3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: CHKKDHVFIR DEAGHGD. It is sometimes possible for the material contained within the vial of "JIK/TAOK3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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