SDS-Page
(Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane: Mouse lung tissue lysate, Primary antibody:ISCU Antibody at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds)
Rabbit anti-Human, Mouse ISCU Polyclonal Antibody | anti-ISCU antibody
ISCU Antibody
Gene Names
ISCU; HML; ISU2; NIFU; NIFUN; hnifU; 2310020H20Rik
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Antigen affinity purification
Synonyms
ISCU; Polyclonal Antibody; ISCU Antibody; HML; ISU2; NIFU; NIFUN; hnifU; 2310020H20Rik; anti-ISCU antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Antigen affinity purification
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-ISCU antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Fusion protein of human ISCU
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C for 1 year.
SDS-Page
(Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane: Mouse lung tissue lysate, Primary antibody:ISCU Antibody at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds)
SDS-Page
(Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane: Mouse lung tissue lysate, Primary antibody:ISCU Antibody at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds)
Related Product Information for anti-ISCU antibody
This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.
Product Categories/Family for anti-ISCU antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
17,999 Da
NCBI Official Full Name
Homo sapiens iron-sulfur cluster scaffold homolog (E. coli), mRNA
NCBI Official Synonym Full Names
iron-sulfur cluster scaffold homolog (E. coli)
NCBI Official Symbol
ISCU
NCBI Official Synonym Symbols
HML; ISU2; NIFU; NIFUN; hnifU; 2310020H20Rik
NCBI Protein Information
iron-sulfur cluster assembly enzyme ISCU, mitochondrial; nifU-like protein; NifU-like N-terminal domain containing; IscU iron-sulfur cluster scaffold homolog; nifU-like N-terminal domain-containing protein
UniProt Protein Name
Protein slowmo homolog 2
Protein Family
UniProt Gene Name
SLMO2
UniProt Synonym Gene Names
C20orf45; CGI-107
UniProt Entry Name
SLMO2_HUMAN
NCBI Description
Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria. [provided by RefSeq, Jul 2008]
Research Articles on ISCU
Similar Products
Product Notes
The ISCU slmo2 (Catalog #AAA9434812) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ISCU Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ISCU can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the ISCU slmo2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ISCU, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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