Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (ISCA2 Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the ISCA2 antibody detected the ISCA2 protein (arrow).)

Rabbit anti-Human, mouse ISCA2 Polyclonal Antibody | anti-ISCA2 antibody

ISCA2 Antibody (Center)

Gene Names
ISCA2; ISA2; HBLD1; MMDS4; c14_5557
Reactivity
Human, mouse
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
ISCA2; Polyclonal Antibody; ISCA2 Antibody (Center); Iron-sulfur cluster assembly 2 homolog; mitochondrial; HESB-like domain-containing protein 1; HBLD1; anti-ISCA2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This ISCA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the Central region of human ISCA2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
72-101
Sequence Length
60
Applicable Applications for anti-ISCA2 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(ISCA2 Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the ISCA2 antibody detected the ISCA2 protein (arrow).)

Western Blot (WB) (ISCA2 Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the ISCA2 antibody detected the ISCA2 protein (arrow).)

Immunohistochemistry (IHC)

(ISCA2 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ISCA2 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (ISCA2 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ISCA2 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-ISCA2 antibody
ISCA2 is involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly (By similarity).
Product Categories/Family for anti-ISCA2 antibody
References
Bailey, S.D., et al. Diabetes Care (2010) In press :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16476
NCBI Official Full Name
iron-sulfur cluster assembly 2 homolog, mitochondrial isoform 2
NCBI Official Synonym Full Names
iron-sulfur cluster assembly 2
NCBI Official Symbol
ISCA2
NCBI Official Synonym Symbols
ISA2; HBLD1; MMDS4; c14_5557
NCBI Protein Information
iron-sulfur cluster assembly 2 homolog, mitochondrial
UniProt Protein Name
Iron-sulfur cluster assembly 2 homolog, mitochondrial
UniProt Gene Name
ISCA2
UniProt Synonym Gene Names
HBLD1
UniProt Entry Name
ISCA2_HUMAN

NCBI Description

The protein encoded by this gene is an A-type iron-sulfur cluster (ISC) protein found in mitochondria. The encoded protein appears to be involved in the maturation of mitochondrial iron-sulfur proteins. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

Uniprot Description

ISCA2: Involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly. Belongs to the HesB/IscA family.

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: mitochondrion

Molecular Function: metal ion binding; iron-sulfur cluster binding; structural molecule activity

Biological Process: iron-sulfur cluster assembly

Disease: Multiple Mitochondrial Dysfunctions Syndrome 4

Research Articles on ISCA2

Similar Products

Product Notes

The ISCA2 isca2 (Catalog #AAA9207794) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 72-101. The ISCA2 Antibody (Center) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ISCA2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the ISCA2 isca2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ISCA2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.