Rabbit anti-Human, Mouse ISCA2 Polyclonal Antibody | anti-ISCA2 antibody

ISCA2, ID (ISCA2, HBLD1, Iron-sulfur cluster assembly 2 homolog, mitochondrial, HESB-like domain-containing protein 1) (APC)

Cat. Num. AAA6311016

• Gene Names: ISCA2; ISA2; HBLD1; MMDS4; c14_5557
• Reactivity: Human, Mouse
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ISCA2; Polyclonal Antibody; ID (ISCA2; HBLD1; Iron-sulfur cluster assembly 2 homolog; mitochondrial; HESB-like domain-containing protein 1) (APC); HESB-like domain-containing protein 1; anti-ISCA2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-ISCA2 antibody: Immunohistochemistry (IHC), FLISA, Western Blot (WB)
• Application Notes: IHC: 1:50-100; FLISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: ISCA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-109 amino acids from the Central region of human ISCA2.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(ISCA2 Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the ISCA2 antibody detected the ISCA2 protein (arrow).)

Immunohistochemistry (IHC)

(ISCA2 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ISCA2 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-ISCA2 antibody

ISCA2 is involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly (By similarity).

Product Categories/Family for anti-ISCA2 antibody

Antibodies; Mitochondrial Proteins

References

Bailey, S.D., et al. Diabetes Care (2010). In press: Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009).

NCBI and Uniprot Product Information

• NCBI GI #: 160420328
• NCBI GeneID: 122961
• NCBI Accession #: NP_919255.2
• NCBI GenBank Nucleotide #: NM_194279.3
• UniProt Accession #: Q86U28; Q8IYZ0; Q96BB2; A6NFF1; A8K3W3; G3V291
• Molecular Weight: 6,211 Da
• NCBI Official Full Name: iron-sulfur cluster assembly 2 homolog, mitochondrial isoform 1
• NCBI Official Synonym Full Names: iron-sulfur cluster assembly 2
• NCBI Official Symbol: ISCA2
• NCBI Official Synonym Symbols: ISA2; HBLD1; MMDS4; c14_5557
• NCBI Protein Information: iron-sulfur cluster assembly 2 homolog, mitochondrial
• UniProt Protein Name: Iron-sulfur cluster assembly 2 homolog, mitochondrial
• Protein Family: Iron-sulfur cluster assembly
• UniProt Gene Name: ISCA2
• UniProt Synonym Gene Names: HBLD1
• UniProt Entry Name: ISCA2_HUMAN

NCBI Description

The protein encoded by this gene is an A-type iron-sulfur cluster (ISC) protein found in mitochondria. The encoded protein appears to be involved in the maturation of mitochondrial iron-sulfur proteins. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]