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Western Blot (Western Blot analysis using IRX3 antibodyIRX3 antibody used at 0.2-1 ug/ml to detect target protein.)

Rabbit IRX3 Polyclonal Antibody | anti-IRX3 antibody

IRX3 antibody

Gene Names
Irx3; AI894186
Applications
Western Blot
Synonyms
IRX3; Polyclonal Antibody; IRX3 antibody; Polyclonal IRX3; Anti-IRX3; IRX 3; IRX-3; anti-IRX3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Form/Format
Lyophilized powder. Add 100 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration
1 mg/ml (varies by lot)
Sequence Length
507
Applicable Applications for anti-IRX3 antibody
Western Blot (WB)
Application Notes
WB: 5 ug/ml
Biological Significance
IRX3 is a member of the Iroquois homeobox gene family that encodes a protein known for its essential role in spinal cord development.
Cross-Reactivity
Mouse, Rat, Bovine, Dog
Immunogen
IRX3 antibody was raised in rabbit using the N terminal of IRX3 as the immunogen
Preparation and Storage
Store at 4 degree C, following reconstitution, aliquot and store at -20 degree C. Avoid repeated freeze-thaw cycles.

Western Blot

(Western Blot analysis using IRX3 antibodyIRX3 antibody used at 0.2-1 ug/ml to detect target protein.)

Western Blot (Western Blot analysis using IRX3 antibodyIRX3 antibody used at 0.2-1 ug/ml to detect target protein.)
Related Product Information for anti-IRX3 antibody
Rabbit polyclonal IRX3 antibody
Product Categories/Family for anti-IRX3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
54,893 Da
NCBI Official Full Name
iroquois-class homeodomain protein IRX-3 isoform 2
NCBI Official Synonym Full Names
Iroquois related homeobox 3
NCBI Official Symbol
Irx3
NCBI Official Synonym Symbols
AI894186
NCBI Protein Information
iroquois-class homeodomain protein IRX-3
UniProt Protein Name
Iroquois-class homeodomain protein IRX-3
UniProt Gene Name
Irx3
UniProt Synonym Gene Names
Irxb1
UniProt Entry Name
IRX3_MOUSE

Uniprot Description

IRX3: Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells. Belongs to the TALE/IRO homeobox family.

Protein type: DNA-binding

Cellular Component: axon; cytoplasm; nucleus

Molecular Function: DNA binding; sequence-specific DNA binding

Biological Process: negative regulation of neuron differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; multicellular organismal development; mesoderm development; kidney development; positive regulation of neuron differentiation

Research Articles on IRX3

Similar Products

Product Notes

The IRX3 irx3 (Catalog #AAA834818) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IRX3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 5 ug/ml. Researchers should empirically determine the suitability of the IRX3 irx3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IRX3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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