Rabbit anti-Human, Mouse IRF9 Polyclonal Antibody | anti-IRF9 antibody

IRF9 Antibody

Cat. Num. AAA7104937

• Gene Names: IRF9; p48; IRF-9; ISGF3; ISGF3G
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot
• Purity: >95%, Protein G purified
• Synonyms: IRF9; Polyclonal Antibody; IRF9 Antibody; Interferon regulatory factor 9; IRF-9; IFN-alpha-responsive transcription factor subunit; ISGF3 p48 subunit; Interferon-stimulated gene factor 3 gamma; ISGF-3 gamma; Transcriptional regulator ISGF3 subunit gamma; ISGF3G; anti-IRF9 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 393

• Applicable Applications for anti-IRF9 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: WB: 1:500-1:5000
• Immunogen: Recombinant Human Interferon regulatory factor 9 protein (44-180AA)
• Conjugation: Non-conjugated
• Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western BlotPositive WB detected in: Mouse liver tissueAll lanes: IRF9 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 44 KDaObserved band size: 44 KDa)

Related Product Information for anti-IRF9 antibody

Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Product Categories/Family for anti-IRF9 antibody

Epigenetics and Nuclear Signaling; Immunology

NCBI and Uniprot Product Information

• NCBI GI #: 25282407
• NCBI GeneID: 10379
• NCBI Accession #: NP_006075.3
• NCBI GenBank Nucleotide #: NP_006075.3
• UniProt Accession #: Q00978; D3DS61
• Molecular Weight: 43,696 Da
• NCBI Official Full Name: interferon regulatory factor 9
• NCBI Official Synonym Full Names: interferon regulatory factor 9
• NCBI Official Symbol: IRF9
• NCBI Official Synonym Symbols: p48; IRF-9; ISGF3; ISGF3G
• NCBI Protein Information: interferon regulatory factor 9
• UniProt Protein Name: Interferon regulatory factor 9
• Protein Family: Interferon regulatory factor
• UniProt Gene Name: IRF9
• UniProt Synonym Gene Names: ISGF3G; IRF-9; ISGF-3 gamma

Uniprot Description

Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.