Western Blot (WB)
(Western blot analysis of lysate from rat brain tissue, using Mouse Insrr Antibody (C-term). MBS9204655 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.)
Rabbit anti-Rat Insrr Polyclonal Antibody | anti-Insrr antibody
Mouse Insrr Antibody (C-term)
Western Blot (WB)
(Western blot analysis of lysate from rat brain tissue, using Mouse Insrr Antibody (C-term). MBS9204655 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.)
Western Blot (WB)
(Western blot analysis of lysate from rat brain tissue, using Mouse Insrr Antibody (C-term). MBS9204655 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.)
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Kitamura T.,et al.Mol. Cell. Biol. 21:5624-5630(2001).
Deyev I.E.,et al.Cell Metab. 13:679-689(2011).
NCBI and Uniprot Product Information
Uniprot Description
IRR: Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB. Probable tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
Protein type: EC 2.7.10.1; Membrane protein, integral; Protein kinase, TK; Kinase, protein; Protein kinase, tyrosine (receptor); TK group; InsR family
Cellular Component: membrane; integral to plasma membrane; integral to membrane; receptor complex
Molecular Function: transferase activity; protein-tyrosine kinase activity; insulin receptor substrate binding; transferase activity, transferring phosphorus-containing groups; nucleotide binding; phosphoinositide 3-kinase binding; transmembrane receptor protein tyrosine kinase activity; kinase activity; ATP binding; protein kinase activity
Biological Process: peptidyl-tyrosine phosphorylation; male sex determination; protein amino acid autophosphorylation; actin cytoskeleton reorganization; signal transduction; phosphorylation; protein amino acid phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway
Research Articles on Insrr
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Product Notes
The Insrr insrr (Catalog #AAA9204655) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Mouse Insrr Antibody (C-term) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Insrr can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Insrr insrr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Insrr, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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