Rabbit anti-Human INSL3 Polyclonal Antibody | anti-INSL3 antibody

INSL3 Antibody

Cat. Num. AAA7122874

• Gene Names: INSL3; RLF; RLNL; ley-I-L
• Reactivity: Human
• Applications: Immunohistochemistry, ELISA
• Purity: Affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
• Synonyms: INSL3; Polyclonal Antibody; INSL3 Antibody; Insulin-like 3 (Leydig insulin-like peptide) (Ley-I-L) (Relaxin-like factor) [Cleaved into: Insulin-like 3 B chain; Insulin-like 3 A chain]; anti-INSL3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
• Form/Format: Liquid; In Phosphate Buffered Saline, pH 7.4, Containing 0.02% Sodium Azide as Preservative and 50% Glycerol.

• Applicable Applications for anti-INSL3 antibody: Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
• Application Notes: IHC-P: 1:50-300; ELISA: 1:10000-20000
• Immunogen: Synthetic peptide from human protein at AA range: 10-50
• Immunogen Species: Human
• Conjugate: Non-conjugated
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:200)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:200)

Product Categories/Family for anti-INSL3 antibody

Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 388240756
• NCBI GeneID: 3640
• NCBI Accession #: NP_001252516.1
• NCBI GenBank Nucleotide #: NM_001265587.1
• UniProt Accession #: P51460; Q3KPI5; Q3KPI6; Q6YNB5; Q9UEA2; Q9UPH6; B4DZ72; G3XAG0
• Molecular Weight: 16,872 Da
• NCBI Official Full Name: insulin-like 3 isoform 1
• NCBI Official Synonym Full Names: insulin like 3
• NCBI Official Symbol: INSL3
• NCBI Official Synonym Symbols: RLF; RLNL; ley-I-L
• NCBI Protein Information: insulin-like 3
• UniProt Protein Name: Insulin-like 3
• Protein Family: Insulin
• UniProt Gene Name: INSL3
• UniProt Synonym Gene Names: RLF; RLNL; Ley-I-L

NCBI Description

This gene encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that this gene may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in this gene may lead to cryptorchidism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2012]

Uniprot Description

Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.