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Rabbit anti-Mouse Induced myeloid leukemia cell differentiation protein Mcl-1 homolog Polyclonal Antibody | anti-Mcl-1 antibody

Rabbit anti-mouse Induced myeloid leukemia cell differentiation protein Mcl-1 homolog polyclonal Antibody

Gene Names
Mcl1; Mcl-1; AW556805
Reactivity
Mouse
Applications
ELISA
Purity
Caprylic Acid Ammonium Sulfate Precipitation Purified
Synonyms
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Polyclonal Antibody; Rabbit anti-mouse Induced myeloid leukemia cell differentiation protein Mcl-1 homolog polyclonal Antibody; Bcl-2-related protein EAT/mcl1; Mcl1; anti-Mcl-1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Sequence Length
331
Applicable Applications for anti-Mcl-1 antibody
ELISA (EIA)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant mouse Induced myeloid leukemia cell differentiation protein Mcl-1 homolog protein
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-Mcl-1 antibody
Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 2 has antiapoptotic activity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
30,930 Da
NCBI Official Full Name
induced myeloid leukemia cell differentiation protein Mcl-1 homolog
NCBI Official Synonym Full Names
myeloid cell leukemia sequence 1
NCBI Official Symbol
Mcl1
NCBI Official Synonym Symbols
Mcl-1; AW556805
NCBI Protein Information
induced myeloid leukemia cell differentiation protein Mcl-1 homolog
UniProt Protein Name
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
UniProt Gene Name
Mcl1
UniProt Entry Name
MCL1_MOUSE

Uniprot Description

MCL1: a myeloid cell leukemia protein of the Bcl-2 family of proteins. Two alternatively spliced transcripts encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.

Protein type: Membrane protein, integral; Inhibitor; Mitochondrial; Channel, misc.; Apoptosis

Cellular Component: cytoplasm; cytosol; integral to membrane; membrane; mitochondrial matrix; mitochondrial outer membrane; mitochondrion; nucleus

Molecular Function: BH domain binding; BH3 domain binding; protein binding; protein dimerization activity; protein heterodimerization activity; protein homodimerization activity

Biological Process: apoptosis; apoptotic mitochondrial changes; cell differentiation; DNA damage response, signal transduction resulting in induction of apoptosis; multicellular organismal development; negative regulation of apoptosis; regulation of apoptosis; response to cytokine stimulus

Research Articles on Mcl-1

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Product Notes

The Mcl-1 mcl1 (Catalog #AAA1488301) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-mouse Induced myeloid leukemia cell differentiation protein Mcl-1 homolog polyclonal Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Induced myeloid leukemia cell differentiation protein Mcl-1 homolog can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the Mcl-1 mcl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Induced myeloid leukemia cell differentiation protein Mcl-1 homolog, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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