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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human tonsil tissue using IL36A Polyclonal Antibody at dilution of 1:35(×200))

Rabbit anti-Human IL36A Polyclonal Antibody | anti-IL36A antibody

IL36A Polyclonal Antibody

Gene Names
IL36A; FIL1; FIL1E; IL1F6; IL-1F6; IL1(EPSILON); FIL1(EPSILON)
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
IL36A; Polyclonal Antibody; IL36A Polyclonal Antibody; FIL1; FIL1 epsilon; FIL1(EPSILON); FIL1E; IL 1 epsilon; IL 1F6; IL 1H1; IL-1 epsilon; IL-1F6; IL1E; IL1F6; IL1RP2; Interleukin 1 epsilon; Interleukin 1 family member 6 (epsilon); Interleukin 1 family member 6; Interleukin 36 alpha; Interleukin-1 epsilon; Interleukin-1 family member 6; MGC129552; MGC129553; MGC151479; MGC151481; OTTMUSP00000012798; RP23-176J12.4; anti-IL36A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
0.96mg/mL (varies by lot)
Sequence Length
158
Applicable Applications for anti-IL36A antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:25-1:100
ELISA: 1:5000-1:10000
Immunogen
Synthetic peptide of human IL36A
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human tonsil tissue using IL36A Polyclonal Antibody at dilution of 1:35(×200))

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human tonsil tissue using IL36A Polyclonal Antibody at dilution of 1:35(×200))
Related Product Information for anti-IL36A antibody
IL36A (Interleukin 36, Alpha) is a Protein Coding gene. Diseases associated with IL36A include Psoriasis. Among its related pathways are Innate Immune System and Toll-Like receptor Signaling Pathways. GO annotations related to this gene include cytokine activity and interleukin-1 receptor binding. An important paralog of this gene is IL36G.The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients.
Product Categories/Family for anti-IL36A antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
interleukin-36 alpha
NCBI Official Synonym Full Names
interleukin 36 alpha
NCBI Official Symbol
IL36A
NCBI Official Synonym Symbols
FIL1; FIL1E; IL1F6; IL-1F6; IL1(EPSILON); FIL1(EPSILON)
NCBI Protein Information
interleukin-36 alpha
UniProt Protein Name
Interleukin-36 alpha
Protein Family
UniProt Gene Name
IL36A
UniProt Synonym Gene Names
FIL1E; IL1E; IL1F6; IL-1 epsilon; IL-1F6
UniProt Entry Name
IL36A_HUMAN

NCBI Description

The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients. [provided by RefSeq, Nov 2015]

Uniprot Description

IL1F6: Belongs to the IL-1 family.

Protein type: Cytokine

Chromosomal Location of Human Ortholog: 2q12-q14.1

Cellular Component: extracellular space; extracellular region

Molecular Function: interleukin-1 receptor binding; cytokine activity

Biological Process: cytokine and chemokine mediated signaling pathway; positive regulation of interleukin-6 production; innate immune response; immune response; inflammatory response

Research Articles on IL36A

Similar Products

Product Notes

The IL36A il36a (Catalog #AAA2561918) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL36A Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL36A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:25-1:100 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the IL36A il36a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL36A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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