Western Blot
(Western blot analysis on D3 using anti- IL1RL1 polyclonal antibody.)
anti-Mouse IL1RL1 Polyclonal Antibody | anti-IL1RL1 antibody
IL1RL1 Antibody
Gene Names
Il1rl1; T1; St2; DER4; Ly84; ST2L; Fit-1; T1/ST2; St2-rs1
Reactivity
Mouse
Applications
Western Blot
Purity
Affinity purified
Synonyms
IL1RL1; Polyclonal Antibody; IL1RL1 Antibody; anti-IL1RL1 antibody
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to mouse IL1RL1.
Purity/Purification
Affinity purified
Form/Format
1*TBS (pH7.4), 0.5%BSA, 25% Glycerol.
Sequence Length
567
Applicable Applications for anti-IL1RL1 antibody
Western Blot (WB)
Application Notes
WB: 1:250
Preservative
0.05% Sodium Azide.
Cellular Localization
Cell Membrane
Positive Control
D3
Preparation and Storage
Store at +4 degree C after thawing. Aliquot store at-20 degree C or-80 degree C. Avoid repeated freeze/thaw cycles.
Western Blot
(Western blot analysis on D3 using anti- IL1RL1 polyclonal antibody.)
Western Blot
(Western blot analysis on D3 using anti- IL1RL1 polyclonal antibody.)
Related Product Information for anti-IL1RL1 antibody
ST2 known as IL1RL1, a membrane protein, belongs to the interleukin-1 receptor family with three Ig-like C2-type (immunoglobulin-like) domains and a TIR domain. Predominantly ST2 expressed in hematopoietic tissues, and in macrophage, erythroid, epithelial and fibroblast cell lines. ST2 is a receptor for interleukin-33 (IL-33) which upon stimulation recruits the signaling molecules MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8.
References
1. "Alternative promoter usage of the Fos-responsive gene Fit-1 generates mRNA isoforms coding for either secreted or membrane-bound proteins related to the IL-1 receptor."Bergers G., Reikersdorfer A., Braselmann S., Graninger P., Busslinger M.EMBO J. 13:1176-1188(1994). 2. "The IL-33/ST2 pathway: therapeutic target and novel biomarker."Kakkar R, Lee RT.Nat ?Rev Drug Discov. 2008 Oct; 7(10):827-40. Review.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
40kDa
NCBI Official Full Name
interleukin-1 receptor-like 1 isoform a
NCBI Official Synonym Full Names
interleukin 1 receptor-like 1
NCBI Official Symbol
Il1rl1
NCBI Official Synonym Symbols
T1; St2; DER4; Ly84; ST2L; Fit-1; T1/ST2; St2-rs1
NCBI Protein Information
interleukin-1 receptor-like 1
UniProt Protein Name
Interleukin-1 receptor-like 1
Protein Family
UniProt Gene Name
Il1rl1
UniProt Synonym Gene Names
Ly84; St2; Ste2
Uniprot Description
Receptor for interleukin-33 (IL-33); signaling requires association of the coreceptor IL1RAP (PubMed:18450470, PubMed:17675517). Its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8 (). Possibly involved in helper T-cell function.
Research Articles on IL1RL1
Similar Products
Product Notes
The IL1RL1 il1rl1 (Catalog #AAA856836) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The IL1RL1 Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's IL1RL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:250. Researchers should empirically determine the suitability of the IL1RL1 il1rl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL1RL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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