Rabbit anti-Mouse IL17RB Polyclonal Antibody | anti-IL17RB antibody
Anti-IL17RB Antibody, Rabbit Polyclonal
Gene Names
Il17rb; Evi27; Il17br; IL-17ER; IL17RH1; IL-17Rh1
Reactivity
Mouse
Applications
ELISA
Purity
Protein A & Antigen Affinity
Synonyms
IL17RB; Polyclonal Antibody; Anti-IL17RB Antibody; Rabbit Polyclonal; IL17BR/IL17RB/IL-17 Receptor B Antibody; Rabbit PAb; Antigen Affinity Purified; interleukin 17 receptor B; Anti-Evi27 Antibody; Anti-IL-17ER Antibody; Anti-IL-17Rh1 Antibody; Anti-Il17br Antibody; Anti-IL17RH1 Antibody; anti-IL17RB antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Mouse IL17BR/IL17RB/IL-17 Receptor B
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-IL17RB antibody
ELISA (EIA)
Application Notes
ELISA: 1:5000-1:10,000
Immunogen
Recombinant Mouse IL17BR/IL17RB/IL-17 Receptor B protein
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with purified, recombinant Mouse IL17BR/IL17RB/IL-17 Receptor B. IL17BR/IL17RB/IL-17 Receptor B specific IgG was purified by Mouse IL17BR/IL17RB/IL-17 Receptor B affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-IL17RB antibody
IL17RB (Interleukin 17 Receptor B) is a Protein Coding gene. IL17RB is the receptor for IL17E, the only member of the IL17 family promoting Th2 reactions. IL17RB is induced on human macrophages by IL4 and enhanced by TGFbeta. Overexpression of IL17RB is associated with poor prognosis and the short survival of breast cancer patients.IL17RB/IL17B signaling triggers a substantial increase in cell growth, proliferation, and migration through the activation of NF-kappaB as well as the up-regulation of the Bcl-2. IL17RB may be the only gene expressed in CD4+ T cells whose transcript measurement is correlated with the variation in IgE level in asthmatics. Diseases associated with IL17RB include Chronic Mucocutaneous Candidiasis and Seborrheic Infantile Dermatitis.
Product Categories/Family for anti-IL17RB antibody
References
Rickel EA, et al.. (2008) Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities. J Immunol. 181(6): 4299-310.Stock P, et al.. (2009) Induction of airway hyperreactivity by IL-25 is dependent on a subset of invariant NKT cells expressing IL-17RB. J Immunol. 182(8): 5116-22.Wang H, et al.. (2010) Allergen challenge of peripheral blood mononuclear cells from patients with seasonal allergic rhinitis increases IL-17RB, which regulates basophil apoptosis and degranulation. Clin Exp Allergy. 40(8): 1194-202.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
57.1kDa (511aa) 57-70KDa (SDS-PAGE under reducing conditions.)
NCBI Official Full Name
interleukin-17 receptor B
NCBI Official Synonym Full Names
interleukin 17 receptor B
NCBI Official Symbol
Il17rb
NCBI Official Synonym Symbols
Evi27; Il17br; IL-17ER; IL17RH1; IL-17Rh1
NCBI Protein Information
interleukin-17 receptor B
UniProt Protein Name
Interleukin-17 receptor B
Protein Family
UniProt Gene Name
Il17rb
UniProt Synonym Gene Names
Evi27; Il17br; IL-17 receptor B; IL-17RB; IL-17ER; IL-17Rh1; IL17Rh1; IL-17B receptor
Uniprot Description
Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.
Research Articles on IL17RB
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Product Notes
The IL17RB il17rb (Catalog #AAA8112325) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-IL17RB Antibody, Rabbit Polyclonal reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's IL17RB can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 1:5000-1:10,000. Researchers should empirically determine the suitability of the IL17RB il17rb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL17RB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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