Western Blot (WB)
(Western Blot analysis of IL17C expression in transfected 293T cell line by IL17C polyclonal antibody. Lane 1: IL17C transfected lysate (21.8kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human IL17C Polyclonal Antibody | anti-IL17C antibody
IL17C (Interleukin-17C, IL-17C, Cytokine CX2, UNQ561/PRO1122) (Biotin)
Western Blot (WB)
(Western Blot analysis of IL17C expression in transfected 293T cell line by IL17C polyclonal antibody. Lane 1: IL17C transfected lysate (21.8kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of IL17C expression in transfected 293T cell line by IL17C polyclonal antibody. Lane 1: IL17C transfected lysate (21.8kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. [provided by RefSeq, Jul 2008]
Uniprot Description
Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases.
Research Articles on IL17C
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Product Notes
The IL17C il17c (Catalog #AAA6382620) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL17C (Interleukin-17C, IL-17C, Cytokine CX2, UNQ561/PRO1122) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL17C can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the IL17C il17c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL17C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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