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Western Blot (WB) (Western blot detection of IL-6 in T47D, COS7 and Hela cell lysates using IL-6 rabbit pAb (1:3000 diluted).Predicted band size:23kDa.Observed band size:23kDa.)

Rabbit IL-6 Polyclonal Antibody | anti-IL-6 antibody

Anti-IL-6 Rabbit pAb

Gene Names
IL6; CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2
Reactivity
Human, Monkey
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Affinity Purified
Synonyms
IL-6; Polyclonal Antibody; Anti-IL-6 Rabbit pAb; Interleukin BSF 2; B cell differentiation factor; B cell stimulatory factor 2; B-cell stimulatory factor 2; BSF 2; BSF-2; BSF2; CDF; CTL differentiation factor; Hepatocyte stimulatory factor; HGF; HSF; Hybridoma growth factor; Hybridoma growth factor Interferon beta-2; IFN-beta-2; IFNB2; IL 6; IL6; IL6_HUMAN; Interferon beta 2; Interferon beta-2; Interleukin 6; Interleukin 6 (interferon beta 2); Interleukin-6; anti-IL-6 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Monkey
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Sequence Length
212
Applicable Applications for anti-IL-6 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) Paraffin
Application Notes
WB: 1:500-1:2000
IHC-p: 1:100-1:300
ELISA: 1:20000
Immunogen
Synthesized peptide derived from IL-6. at AA range: INTERNAL.
Subcellular Location
Secreted

Western Blot (WB)

(Western blot detection of IL-6 in T47D, COS7 and Hela cell lysates using IL-6 rabbit pAb (1:3000 diluted).Predicted band size:23kDa.Observed band size:23kDa.)

Western Blot (WB) (Western blot detection of IL-6 in T47D, COS7 and Hela cell lysates using IL-6 rabbit pAb (1:3000 diluted).Predicted band size:23kDa.Observed band size:23kDa.)

Western Blot (WB)

(Western Blot analysis of K562 cells using IL-6 Polyclonal Antibody.)

Western Blot (WB) (Western Blot analysis of K562 cells using IL-6 Polyclonal Antibody.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:100)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:100)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:100)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:100)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23kDa
NCBI Official Full Name
interleukin-6 isoform 1
NCBI Official Synonym Full Names
interleukin 6
NCBI Official Symbol
IL6
NCBI Official Synonym Symbols
CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2
NCBI Protein Information
interleukin-6
UniProt Protein Name
Interleukin-6
UniProt Gene Name
IL6
UniProt Synonym Gene Names
IFNB2; IL-6; BSF-2; CDF; IFN-beta-2

NCBI Description

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Uniprot Description

Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.

Research Articles on IL-6

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Product Notes

The IL-6 il6 (Catalog #AAA477486) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-IL-6 Rabbit pAb reacts with Human, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's IL-6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) Paraffin. WB: 1:500-1:2000 IHC-p: 1:100-1:300 ELISA: 1:20000. Researchers should empirically determine the suitability of the IL-6 il6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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