Western Blot (WB)
(Western blot analysis of IL-22RA2 expression in HeLa (A), MCF7 (B), mouse heart (C), rat heart (D) whole cell lysates.)
Rabbit IL-22RA2 Polyclonal Antibody | anti-IL22RA2 antibody
Anti-IL-22RA2 Antibody
Western Blot (WB)
(Western blot analysis of IL-22RA2 expression in HeLa (A), MCF7 (B), mouse heart (C), rat heart (D) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of IL-22RA2 expression in HeLa (A), MCF7 (B), mouse heart (C), rat heart (D) whole cell lysates.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the class II cytokine receptor family. The encoded soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. The encoded protein may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]
Uniprot Description
IL22RA2: Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses. Belongs to the type II cytokine receptor family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 6q23.3
Cellular Component: extracellular space; integral to membrane; plasma membrane; cytosol
Molecular Function: interleukin-22 binding; interleukin-22 receptor activity
Biological Process: regulation of tyrosine phosphorylation of Stat3 protein; cytokine and chemokine mediated signaling pathway; negative regulation of inflammatory response
Research Articles on IL22RA2
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Product Notes
The IL22RA2 il22ra2 (Catalog #AAA820140) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-IL-22RA2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's IL-22RA2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB (1/500 - 1/1000). Researchers should empirically determine the suitability of the IL22RA2 il22ra2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-22RA2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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