Western Blot (WB)
(COPZ1 Antibody (N-term) western blot analysis in L929 cell line lysates (35ug/lane).This demonstrates the COPZ1 antibody detected the COPZ1 protein (arrow).)
Rabbit COPZ1 Polyclonal Antibody | anti-COPZ1 antibody
COPZ1 Antibody (N-term)
Western Blot (WB)
(COPZ1 Antibody (N-term) western blot analysis in L929 cell line lysates (35ug/lane).This demonstrates the COPZ1 antibody detected the COPZ1 protein (arrow).)
Western Blot (WB)
(COPZ1 Antibody (N-term) western blot analysis in L929 cell line lysates (35ug/lane).This demonstrates the COPZ1 antibody detected the COPZ1 protein (arrow).)
Western Blot (WB)
(COPZ1 Antibody (N-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the COPZ1 antibody detected the COPZ1 protein (arrow).)
Western Blot (WB)
(COPZ1 Antibody (N-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the COPZ1 antibody detected the COPZ1 protein (arrow).)
The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Lippincott-Schwartz, J., et al. Trends Cell Biol. 16 (10), E1-E4 (2006) :
Wegmann, D., et al. Mol. Cell. Biol. 24(3):1070-1080(2004)
Futatsumori, M., et al. J. Biochem. 128(5):793-801(2000)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a subunit of the cytoplasmic coatamer protein complex, which is involved in autophagy and intracellular protein trafficking. The coatomer protein complex is comprised of seven subunits and functions as the coat protein of coat protein complex (COP)I-vesicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Uniprot Description
COPZ1: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Belongs to the adaptor complexes small subunit family.
Protein type: Motility/polarity/chemotaxis; Adaptor/scaffold
Chromosomal Location of Human Ortholog: 12q13.2-q13.3
Cellular Component: COPI vesicle coat; cytosol
Biological Process: intra-Golgi vesicle-mediated transport; intracellular protein transport; COPI coating of Golgi vesicle; retrograde vesicle-mediated transport, Golgi to ER
Research Articles on COPZ1
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Product Notes
The COPZ1 copz1 (Catalog #AAA9214751) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 24-53. The COPZ1 Antibody (N-term) reacts with Human, mouse (Predicted Reactivity: Bovine) and may cross-react with other species as described in the data sheet. AAA Biotech's COPZ1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the COPZ1 copz1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COPZ1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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