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Rabbit anti-Mouse IL-12 Polyclonal Antibody | anti-IL12A antibody

Anti-IL-12 Antibody, Rabbit Polyclonal

Reactivity
Mouse
Applications
ELISA
Purity
Protein A
Synonyms
IL-12; Polyclonal Antibody; Anti-IL-12 Antibody; Rabbit Polyclonal; IL-12 (IL12A & IL12B Heterodimer) Antibody; Rabbit PAb; interleukin 12A; Anti-Il-12a Antibody; Anti-Il-12b Antibody; Anti-IL-12p35 Antibody; Anti-Il-12p40 Antibody; Anti-Il12p40 Antibody; Anti-Ll12a Antibody; Anti-p35 Antibody; Anti-p40 Antibody; anti-IL12A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Mouse IL-12 (IL12A & IL12B Heterodimer)
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-IL12A antibody
ELISA (EIA)
Application Notes
ELISA: 1:1000-1:2000
Immunogen
Recombinant Mouse IL-12 (IL12A & IL12B Heterodimer) Protein
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with purified, recombinant Mouse IL-12 (IL12A & IL12B Heterodimer) (rM IL-12 (IL12A & IL12B Heterodimer)). Total IgG was purified by Protein A affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Product Categories/Family for anti-IL12A antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
24,179 Da
NCBI Official Full Name
interleukin-12 subunit alpha isoform 1
UniProt Protein Name
Interleukin-12 subunit alpha
Protein Family
UniProt Gene Name
Il12a
UniProt Synonym Gene Names
IL-12A; CLMF p35
UniProt Entry Name
IL12A_MOUSE

Uniprot Description

IL12A: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine- activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-6 superfamily.

Protein type: Secreted, signal peptide; Cytokine; Secreted

Cellular Component: extracellular space; interleukin-12 complex; cytoplasm; extracellular region

Molecular Function: interleukin-27 binding; growth factor activity; interleukin-12 beta subunit binding; protein heterodimerization activity; cytokine activity; interleukin-12 receptor binding

Biological Process: positive regulation of NK T cell activation; cell migration; positive regulation of cell adhesion; negative regulation of smooth muscle cell proliferation; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; positive regulation of T cell mediated cytotoxicity; positive regulation of tyrosine phosphorylation of Stat4 protein; response to lipopolysaccharide; defense response to protozoan; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of natural killer cell activation; response to UV-B; positive regulation of interferon-gamma production; negative regulation of interleukin-17 production; positive regulation of mononuclear cell proliferation; positive regulation of T cell differentiation; positive regulation of lymphocyte proliferation; positive regulation of T cell proliferation; immune response; cell cycle arrest

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Product Notes

The IL12A il12a (Catalog #AAA8113338) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-IL-12 Antibody, Rabbit Polyclonal reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's IL-12 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 1:1000-1:2000. Researchers should empirically determine the suitability of the IL12A il12a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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