Rabbit IGFBP1 Polyclonal Antibody | anti-IGFBP1 antibody

Anti-IGFBP1 Antibody

Cat. Num. AAA8242767

• Gene Names: IGFBP1; AFBP; IBP1; PP12; IGF-BP25; hIGFBP-1
• Reactivity: Human, Monkey
• Applications: Western Blot
• Purity: The antibody was purified by affinity chromatography.
• Synonyms: IGFBP1; Polyclonal Antibody; Anti-IGFBP1 Antibody; IBP1; Insulin-like growth factor-binding protein 1; IBP-1; IGF-binding protein 1; IGFBP-1; Placental protein 12; PP12; anti-IGFBP1 antibody

• Host: Rabbit
• Reactivity: Human, Monkey
• Clonality: Polyclonal
• Specificity: Recognizes endogenous levels of IGFBP1 protein.
• Purity/Purification: The antibody was purified by affinity chromatography.
• Form/Format: Liquid in PBS, pH 7.3, 0.2% BSA, and 0.02% Sodium Azide.
• Sequence Length: 259

• Applicable Applications for anti-IGFBP1 antibody: Western Blot (WB)
• Application Notes: Western Blot: (1/500 - 1/1000)
• Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IGFBP1. The exact sequence is proprietary.
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of IGFBP1 expression in HepG2 (A), MCF7 (B) whole cell lysates.)

Related Product Information for anti-IGFBP1 antibody

Rabbit polyclonal antibody to IGFBP1

NCBI and Uniprot Product Information

• NCBI GI #: 124055
• NCBI GeneID: 3484
• UniProt Accession #: P08833; Q8IYP5; A4D2F4; D3DVL9
• Molecular Weight: 27,904 Da
• NCBI Official Full Name: Insulin-like growth factor-binding protein 1
• NCBI Official Synonym Full Names: insulin like growth factor binding protein 1
• NCBI Official Symbol: IGFBP1
• NCBI Official Synonym Symbols: AFBP; IBP1; PP12; IGF-BP25; hIGFBP-1
• NCBI Protein Information: insulin-like growth factor-binding protein 1
• UniProt Protein Name: Insulin-like growth factor-binding protein 1
• Protein Family: Insulin-like growth factor-binding protein
• UniProt Gene Name: IGFBP1
• UniProt Synonym Gene Names: IBP1; IBP-1; IGF-binding protein 1; IGFBP-1; PP12
• UniProt Entry Name: IBP1_HUMAN

NCBI Description

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008]

Uniprot Description

IGFBP1: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7p12.3

Cellular Component: extracellular region; extracellular space

Molecular Function: insulin-like growth factor binding; insulin-like growth factor I binding; insulin-like growth factor II binding

Biological Process: cellular protein metabolic process; insulin receptor signaling pathway; positive regulation of cell growth; regulation of insulin-like growth factor receptor signaling pathway; signal transduction; tissue regeneration; unfolded protein response