Rabbit IGBP1 Polyclonal Antibody | anti-IGBP1 antibody
IGBP1 Antibody
Gene Names
IGBP1; IBP1; ALPHA-4
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
IGBP1; Polyclonal Antibody; IGBP1 Antibody; Alpha 4; B cell signal transduction molecule alpha 4; B-cell signal transduction molecule alpha 4; bA351K23.1 (immunoglobulin binding protein 1 (CD79A)); bA351K23.1; CD79a binding protein 1; CD79a-binding protein 1; IBP 1; IBP1; IGBP 1; Igbp1; IGBP1_HUMAN; Immunoglobulin (CD79A) binding protein 1; Immunoglobulin binding protein 1; Immunoglobulin-binding protein 1; Protein alpha 4; Protein alpha-4; Protein phosphatase 2/4/6 regulatory subunit; Protein phosphatase 2A regulatory subunit alpha 4; Renal carcinoma antigen NY REN 16; Renal carcinoma antigen NY-REN-16; anti-IGBP1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
IGBP1 Antibody detects endogenous levels of IGBP1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-IGBP1 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human IGBP1.
Conjugation
Unconjugated
Similarity
The UIM domain is required for protective effect on PP2A. Belongs to the IGBP1/TAP42 family.
Post Translational Modifications
Phosphorylated.Monoubiquitination by MID1 triggers calpain-mediated cleavage and switches IGBP1 activity from protective to destructive.
Subunit Structure
Interacts with partially folded PPP2CA, but not with the fully active protein. Interacts with PPP2CB, and with PP4 and PP6. Interacts with MID1 and MID2. Interacts with ubiquitin.
Tissue Specificity
Ubiquitously expressed with highest levels in heart, skeletal muscle and pancreas.
Function
Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of the phosphatases PP2A, PP4 and PP6 by protecting their partially folded catalytic subunits from degradative polyubiquitination until they associate with regulatory subunits.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39,222 Da
NCBI Official Full Name
immunoglobulin-binding protein 1
NCBI Official Synonym Full Names
immunoglobulin (CD79A) binding protein 1
NCBI Official Symbol
IGBP1
NCBI Official Synonym Symbols
IBP1; ALPHA-4
NCBI Protein Information
immunoglobulin-binding protein 1; B cell signal transduction molecule alpha 4; B-cell signal transduction molecule alpha 4; CD79a-binding protein 1; bA351K23.1 (immunoglobulin binding protein 1 (CD79A) ); protein alpha-4; protein phosphatase 2/4/6 regulat
UniProt Protein Name
Immunoglobulin-binding protein 1
Protein Family
UniProt Gene Name
IGBP1
UniProt Synonym Gene Names
IBP1; Protein alpha-4
UniProt Entry Name
IGBP1_HUMAN
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Product Notes
The IGBP1 igbp1 (Catalog #AAA9630998) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IGBP1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's IGBP1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the IGBP1 igbp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IGBP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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