Western Blot (WB)
(WB Suggested Anti-IFT74 AntibodyTitration: 1.0 ug/mlPositive Control: MCF7 Whole Cell)
Rabbit IFT74 Polyclonal Antibody | anti-IFT74 antibody
IFT74 antibody - C-terminal region
Western Blot (WB)
(WB Suggested Anti-IFT74 AntibodyTitration: 1.0 ug/mlPositive Control: MCF7 Whole Cell)
Western Blot (WB)
(WB Suggested Anti-IFT74 AntibodyTitration: 1.0 ug/mlPositive Control: MCF7 Whole Cell)
Target Description: The function of this protein remains unknown.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome. [provided by RefSeq, Mar 2017]
Uniprot Description
IFT74: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 9p21.2
Cellular Component: centrosome; cytoplasmic membrane-bound vesicle; nucleus; cilium
Molecular Function: beta-tubulin binding; chromatin binding
Biological Process: Notch signaling pathway; organelle organization and biogenesis; cilium biogenesis; positive regulation of cell adhesion mediated by integrin; positive regulation of transcription from RNA polymerase II promoter; negative regulation of epithelial cell proliferation
Research Articles on IFT74
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Product Notes
The IFT74 ift74 (Catalog #AAA3215447) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IFT74 antibody - C-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's IFT74 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the IFT74 ift74 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: WQHLEQNNFA MKEFIATKSQ ESDYQPIKKN VTKQIAEYNK TIVDALHSTS. It is sometimes possible for the material contained within the vial of "IFT74, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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