Immunohistochemistry (IHC)
(Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit IAPP/Amylin Polyclonal Antibody | anti-IAPP antibody
Anti-IAPP/Amylin Antibody
Gene Names
IAPP; DAP; IAP
Reactivity
HumanPredicted: Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
IAPP/Amylin; Polyclonal Antibody; Anti-IAPP/Amylin Antibody; Rabbit Polyclonal (IgG) to Human IAPP/Amylin; IAPP; Diabetes-associated peptide; Islet amyloid polypeptide; AMYLIN; IAP; Insulinoma amyloid peptide; anti-IAPP antibody
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Predicted: Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Human IAPP/Amylin
Purity/Purification
Affinity Purified
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Sequence Length
89
Applicable Applications for anti-IAPP antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P: 1:100-1:200
WB: 1:500-1:2000
WB: 1:500-1:2000
Immunogen
A synthetic peptide of human IAPP.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
Avoid freeze-thaw cycles.
Avoid freeze-thaw cycles.
Immunohistochemistry (IHC)
(Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))
Western Blot (WB)
(Western blot analysis of extracts of HeLa cells.)
Western Blot (WB)
(Western blot analysis of extracts of HeLa cells.)
Western Blot (WB)
(Western blot analysis of extracts of HeLa cell line, using IAPP antibody.)
Western Blot (WB)
(Western blot analysis of extracts of HeLa cell line, using IAPP antibody.)
Related Product Information for anti-IAPP antibody
IAPP/Amylin is commonly found in pancreatic islets of patientssuffering diabetes mellitus type II, or harboring an insulinoma. Studiessuggest that this protein , like the related beta-amyloid (Abeta)associated with Alzheimer's disease, can induce apoptotic cell-death inparticular cultured cells, an effect that may be relevant to the development of type II diabetes. This protein also exhibits anbactericidal, antimicrobial activity.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
9,806 Da
NCBI Official Full Name
islet amyloid polypeptide preproprotein
NCBI Official Synonym Full Names
islet amyloid polypeptide
NCBI Official Symbol
IAPP
NCBI Official Synonym Symbols
DAP; IAP
NCBI Protein Information
islet amyloid polypeptide
UniProt Protein Name
Islet amyloid polypeptide
Protein Family
UniProt Gene Name
IAPP
UniProt Synonym Gene Names
DAP
NCBI Description
This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity. [provided by RefSeq, Jul 2016]
Uniprot Description
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
Research Articles on IAPP
Similar Products
Product Notes
The IAPP iapp (Catalog #AAA2401933) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-IAPP/Amylin Antibody reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's IAPP/Amylin can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P: 1:100-1:200 WB: 1:500-1:2000. Researchers should empirically determine the suitability of the IAPP iapp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IAPP/Amylin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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