Rabbit I-FABP Polyclonal Antibody | anti-I-FABP antibody

I-FABP Polyclonal Antibody

Cat. Num. AAA9419748

• Gene Names: FABP2; FABPI; I-FABP
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
• Synonyms: I-FABP; Polyclonal Antibody; I-FABP Polyclonal Antibody; Fatty acid-binding protein; intestinal (Fatty acid-binding protein 2) (Intestinal-type fatty acid-binding protein) (I-FABP); anti-I-FABP antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous I-FABP
• Purity/Purification: Affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
• Form/Format: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
• Concentration: 1 mg/ml (varies by lot)

• Applicable Applications for anti-I-FABP antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500-1:2000; IHC: 1:50-300
• Immunogen: Synthetic peptide from human protein at AA range: 90-132
• Immunogen Type: Protein
• Preparation and Storage: Store at -20 degree C

Western Blot (WB)

(Western blot analysis of mouse-brain mouse-spinal-cord lysate, antibody was diluted at 2000. Secondary antibody was diluted at 1:20000)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human-small-intestine, antibody was diluted at 1:200)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human-small-intestine, antibody was diluted at 1:200)

Product Categories/Family for anti-I-FABP antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 194097325
• NCBI GeneID: 2169
• NCBI Accession #: NP_000125.2
• NCBI GenBank Nucleotide #: NM_000134.3
• UniProt Accession #: P12104; Q2NKJ1
• Molecular Weight: 15 kDa
• NCBI Official Full Name: fatty acid-binding protein, intestinal
• NCBI Official Synonym Full Names: fatty acid binding protein 2
• NCBI Official Symbol: FABP2
• NCBI Official Synonym Symbols: FABPI; I-FABP
• NCBI Protein Information: fatty acid-binding protein, intestinal
• UniProt Protein Name: Fatty acid-binding protein, intestinal
• UniProt Gene Name: FABP2
• UniProt Synonym Gene Names: FABPI; I-FABP

NCBI Description

The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. [provided by RefSeq, Jul 2008]

Uniprot Description

FABP2: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Lipid-binding; Transporter

Chromosomal Location of Human Ortholog: 4q26

Cellular Component: cytosol

Molecular Function: protein binding

Biological Process: digestion; triacylglycerol catabolic process