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Rabbit Humanin Polyclonal Antibody | anti-MTRNR2L2 antibody

Rabbit Polyclonal Anti-Humanin Antibody

Gene Names
MTRNR2L2; HN2
Reactivity
Human, Monkey
Applications
ELISA, Immunoprecipitation, Western Blot
Synonyms
Humanin; Polyclonal Antibody; Rabbit Polyclonal Anti-Humanin Antibody; HN; HUNIN; MT-RNR2 antibody; anti-MTRNR2L2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Monkey
Clonality
Polyclonal
Specificity
Will detect all isoforms except Humanin 9.
Form/Format
Affinity Purified Immunoglobulins
Sequence
GFSCLLLSTTATDLPVKRRT
Sequence Length
28
Applicable Applications for anti-MTRNR2L2 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
Recommended Dilution:
ELISA: 1:10,000
Immunoprecipitation: 1:200
Western Blot: 1:500
Dot Blot: 1:10,000
Immunogen
Synthetic peptide corresponding to amino acid region 5-24 on Humanin protein
Preparation and Storage
-20 degree C for long term storage
Related Product Information for anti-MTRNR2L2 antibody
Humanin is a peptide that is 21 or 24 amino acids long whether it is produced in the mitochondria or cytosol respectively (1). Humanin is encoded by the mi16S ribosomal RNA gene MT-RNR2 (2). Humanin is believed to have neuroprotective and cytoprotective effects. Studies have found human in and humanin derivatives increase survival and physiological parameters in Alzheimer's disease models (3). Humanin is also believed to play neuroprotective roles in Huntington's deisease, pnon disease and strokes (4). Humanin may playa role in various other ailments including protection against oxidative stress, atherosclerotic plaque formation, heart attack and diabetes. (5, 6, 7, 8, 9).

The pan-Humanin selective antibodies were generated using a synthetic peptide corresponding to amino acid region 5-24 on human Humanin peptide. The Humanin antibodies are affinity purified over immobilized antigen based affinity chromatography. The purified immunoglobulins are prepared in stabilization buffer for long term storage Antigenic blocking peptides (P-HUMN), and western blot positive control (pC-HUMN) in ready to use SDS-sample buffer are available Antibodies can be conjugated to fluorophores and other secondary enzymes upon request at nominal cost The pan-Humanin selective antibodies will label all Humanin isoforms except Humanin 9. Humanin 9-selective antibody (Please Inquire) is available for detection of only the Humanin 9 isoform.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
humanin-like 2
NCBI Official Synonym Full Names
MT-RNR2-like 2
NCBI Official Symbol
MTRNR2L2
NCBI Official Synonym Symbols
HN2
NCBI Protein Information
humanin-like 2
UniProt Protein Name
Humanin-like 2
Protein Family
UniProt Gene Name
MTRNR2L2
UniProt Synonym Gene Names
HN2
UniProt Entry Name
HMN2_HUMAN

Uniprot Description

MTRNR2L2: Plays a role as a neuroprotective and antiapoptotic factor. Belongs to the humanin family.

Chromosomal Location of Human Ortholog: 5q14.1

Cellular Component: cytoplasm; extracellular region

Research Articles on MTRNR2L2

Similar Products

Product Notes

The MTRNR2L2 mtrnr2l2 (Catalog #AAA541832) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal Anti-Humanin Antibody reacts with Human, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's Humanin can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). Recommended Dilution: ELISA: 1:10,000 Immunoprecipitation: 1:200 Western Blot: 1:500 Dot Blot: 1:10,000. Researchers should empirically determine the suitability of the MTRNR2L2 mtrnr2l2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: GFSCLLLSTT ATDLPVKRRT. It is sometimes possible for the material contained within the vial of "Humanin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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