Immunohistochemistry (IHC)
(Human, Brain, Cerebellum: Formalin-Fixed Paraffin-Embedded (FFPE))
Rabbit HTR6 / 5-HT6 Receptor Polyclonal Antibody | anti-HTR6 antibody
Rabbit Polyclonal to Human HTR6 / 5-HT6 Receptor
Predicted Reactivity: Mouse, Bat, Bovine, Rabbit (at least 90% immunogen sequence identity)
Predicted Reactivity: Mouse, Bat, Bovine, Rabbit (at least 90% immunogen sequence identity)
Immunohistochemistry (IHC)
(Human, Brain, Cerebellum: Formalin-Fixed Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human, Brain, Cerebellum: Formalin-Fixed Paraffin-Embedded (FFPE))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor. [provided by RefSeq, Aug 2013]
Uniprot Description
5-HT(6): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs. Belongs to the G-protein coupled receptor 1 family.
Protein type: Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1
Chromosomal Location of Human Ortholog: 1p36-p35
Cellular Component: integral to plasma membrane; dendrite; plasma membrane; cilium
Molecular Function: protein binding; serotonin receptor activity; histamine receptor activity
Biological Process: response to drug; G-protein signaling, coupled to cyclic nucleotide second messenger; positive regulation of dopamine secretion; synaptic transmission; cerebral cortex cell migration; negative regulation of glutamate secretion; negative regulation of gamma-aminobutyric acid secretion; negative regulation of acetylcholine secretion; learning; serotonin receptor signaling pathway; response to estradiol stimulus; positive regulation of TOR signaling pathway; positive regulation of gamma-aminobutyric acid secretion
Research Articles on HTR6
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Product Notes
The HTR6 htr6 (Catalog #AAA244405) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human HTR6 / 5-HT6 Receptor reacts with Gibbon, Chimpanzee, Dog, Gorilla, Hamster, Horse, Human, Monkey, Rat Predicted Reactivity: Mouse, Bat, Bovine, Rabbit (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's HTR6 / 5-HT6 Receptor can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (10 - 20 ug/ml). Researchers should empirically determine the suitability of the HTR6 htr6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HTR6 / 5-HT6 Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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