Western Blot (WB)
(Western blot analysis of extracts from Human liver tissue, using HRSP12 Antibody. The lane on the left was treated with blocking peptide.)
Rabbit HRSP12 Polyclonal Antibody | anti-HRSP12 antibody
HRSP12 Antibody
Gene Names
RIDA; PSP; P14.5; UK114; HRSP12; hp14.5
Reactivity
Human, RatPredicted: Pig, Zebrafish, Bovine, Dog, Chicken, Xenopus
Applications
Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
HRSP12; Polyclonal Antibody; HRSP12 Antibody; 14.5 kDa translational inhibitor protein; 2-iminobutanoate/2-iminopropanoate deaminase; Heat responsive protein 12; Heat-responsive protein 12; Hrsp12; p14.5; Perchloric acid soluble protein; PSP; Reactive intermediate imine deaminase A homolog; Ribonuclease UK114; RIDA; Translational inhibitor p14.5; Translational inhibitor protein p14.5; UK114; UK114 antigen homolog; UK114_HUMAN; anti-HRSP12 antibody
Host
Rabbit
Reactivity
Human, Rat
Predicted: Pig, Zebrafish, Bovine, Dog, Chicken, Xenopus
Predicted: Pig, Zebrafish, Bovine, Dog, Chicken, Xenopus
Clonality
Polyclonal
Isotype
IgG
Specificity
HRSP12 Antibody detects endogenous levels of HRSP12.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
137
Applicable Applications for anti-HRSP12 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide derived from human HRSP12.
Tissue Specificity
Expressed predominantly in liver and kidney. Lower levels in lung and brain.
Fragment
Fab Fragment
Conjugate
Unconjugated
Subcellular Location
Peroxisome; Mitochondrion; Nucleus
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of extracts from Human liver tissue, using HRSP12 Antibody. The lane on the left was treated with blocking peptide.)
Western Blot (WB)
(Western blot analysis of extracts from Human liver tissue, using HRSP12 Antibody. The lane on the left was treated with blocking peptide.)
Related Product Information for anti-HRSP12 antibody
Description: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.
Subunit Structure: Homotrimer.
Similarity: Belongs to the RutC family.
Subunit Structure: Homotrimer.
Similarity: Belongs to the RutC family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
Observed: 14.5 kDa
Predicted: 15 kDa
Predicted: 15 kDa
NCBI Official Full Name
2-iminobutanoate/2-iminopropanoate deaminase
NCBI Official Synonym Full Names
reactive intermediate imine deaminase A homolog
NCBI Official Symbol
RIDA
NCBI Official Synonym Symbols
PSP; P14.5; UK114; HRSP12; hp14.5
NCBI Protein Information
2-iminobutanoate/2-iminopropanoate deaminase
UniProt Protein Name
Ribonuclease UK114
Protein Family
UniProt Gene Name
HRSP12
UniProt Synonym Gene Names
PSP; p14.5
UniProt Entry Name
UK114_HUMAN
Uniprot Description
HRSP12: Endoribonuclease responsible for the inhibition of the translation by cleaving mRNA. Inhibits cell-free protein synthesis. Cleaves phosphodiester bonds only in single-stranded RNA. Belongs to the RutC family.
Protein type: Hydrolase; EC 3.1.-.-
Chromosomal Location of Human Ortholog: 8q22
Cellular Component: mitochondrion; cytoplasm; nucleus
Molecular Function: endonuclease activity; deaminase activity
Biological Process: regulation of translational termination
Research Articles on HRSP12
Similar Products
Product Notes
The HRSP12 hrsp12 (Catalog #AAA9611823) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HRSP12 Antibody reacts with Human, Rat Predicted: Pig, Zebrafish, Bovine, Dog, Chicken, Xenopus and may cross-react with other species as described in the data sheet. AAA Biotech's HRSP12 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the HRSP12 hrsp12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HRSP12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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