Western Blot (WB)
((1ug/ml) staining of Pig Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat HOXA5 Polyclonal Antibody | anti-HOXA5 antibody
Goat anti-HOXA5 (aa157-168) Antibody
Western Blot: Approx 30kDa band observed in Pig Kidney lysates (calculated MW of 29.3kDa according to Pig NP_001182161.1). Recommended concentration: 1-3ug/ml.
Western Blot (WB)
((1ug/ml) staining of Pig Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
((1ug/ml) staining of Pig Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
NCBI and Uniprot Product Information
NCBI Description
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. [provided by RefSeq, Jul 2008]
Uniprot Description
HOXA5: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3'. Belongs to the Antp homeobox family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 7p15.2
Cellular Component: nucleus
Molecular Function: DNA binding; protein binding; transcription factor activity
Biological Process: alveolus development; anterior/posterior pattern formation; cell migration; embryonic skeletal morphogenesis; multicellular organism growth; negative regulation of angiogenesis; negative regulation of erythrocyte differentiation; positive regulation of apoptosis; positive regulation of myeloid cell differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of mammary gland epithelial cell proliferation; respiratory system process; thyroid gland development; transcription from RNA polymerase II promoter
Research Articles on HOXA5
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Product Notes
The HOXA5 hoxa5 (Catalog #AAA423535) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-HOXA5 (aa157-168) Antibody reacts with Tested: Pig; Expected from sequence similarity: Human, Pig, Cow and may cross-react with other species as described in the data sheet. AAA Biotech's HOXA5 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 2000. Western Blot: Approx 30kDa band observed in Pig Kidney lysates (calculated MW of 29.3kDa according to Pig NP_001182161.1). Recommended concentration: 1-3ug/ml. Researchers should empirically determine the suitability of the HOXA5 hoxa5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: SEQASAQSEP SP. It is sometimes possible for the material contained within the vial of "HOXA5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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