Rabbit HOXA3 Polyclonal Antibody | anti-HOXA3 antibody
Anti-HOXA3 antibody
Western Blot (WB)
(Anti-HOXA3 antibody, MBS175402, Western blottingAll lanes: Anti HOXA3 (MBS175402) at 0.5ug/mlWB: SW620 Whole Cell Lysate at 40ugPredicted bind size: 46KDObserved bind size: 46KD )
Immunohistochemistry (IHC)
(Anti-HOXA3 antibody, MBS175402, IHC(P)IHC(P): Human Pancreatic Cancer Tissue )
Background: HOXA3(HOMEOBOX A3) is a protein that in humans is encoded by the HOXA3 gene, which is also part of the A cluster on chromosome 7. HOXA3 encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Its cytogenetic location is 7q15.2. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA3 protein is able to complement Hoxd3 deficiency when expressed in the context of the Hoxd3 allele.
NCBI and Uniprot Product Information
NCBI Description
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
HOXA3: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 7p15.2
Cellular Component: nucleoplasm
Molecular Function: sequence-specific DNA binding; transcription factor activity
Biological Process: anterior/posterior pattern formation; specification of organ position; organ formation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; thymus development; cartilage development; positive regulation of cell proliferation; glossopharyngeal nerve morphogenesis; thyroid gland development; blood vessel remodeling; angiogenesis; parathyroid gland development; embryonic skeletal morphogenesis
Research Articles on HOXA3
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Product Notes
The HOXA3 hoxa3 (Catalog #AAA175402) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-HOXA3 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HOXA3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the HOXA3 hoxa3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HOXA3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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