HNRPH1 antibody pair

HNRPH1 Antibody Pair

Cat. Num. AAA7041845

• Gene Names: HNRNPH1; HNRPH; HNRPH1; hnRNPH
• Reactivity: Human, Mouse, Guinea Pig, Bovine, Horse, Pig, Dog
• Applications: ELISA
• Synonyms: HNRPH1; Polyclonal Antibody Pair; HNRPH1 Antibody Pair; Heterogeneous nuclear ribonucleoprotein H; hnRNP H; HNRNPH1; HNRPH; HNRPH1 antibody pair

• Host: Capture: Rabbit; Detection: Rabbit
• Reactivity: Human, Mouse, Guinea Pig, Bovine, Horse, Pig, Dog
• Clonality: Polyclonal
• Isotype: Capture: IgG; Detection: IgG
• Form/Format: Liquid
• Concentration: The concentrations and volumes of the antibodies may vary and be lot specific. Details will be on the vial labels. (varies by lot)
• Sequence Length: 449

• Applicable Applications for HNRPH1 antibody pair: Sandwich ELISA (EIA)
• Application Notes: We recommend using the capture antibody at a concentration of 0.3ug/ml and the detection antibody at a concentration of 0.5ug/ml.
• Immunogen Species: Human
• Conjugation: Capture: Non-conjugated; Detection: Biotin conjugated
• Recommended Standard: HeLa cell; (Standards are recommendations only. Compatibility of the standards in the user developed application needs to be established and confirmed by the researcher.
• Storage Buffer: Capture: 50% Glycerol, 0.01M PBS, PH 7.4; Detection: 50% Glycerol, 0.01M PBS, PH 7.4
• Other Note: Immunogen information is company proprietary information. Antibodies are sold as a pair and not available separately.
• Preparation and Storage: Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze/thaw cycles. When stored properly, products should be stable for at least 5 months.

NCBI and Uniprot Product Information

• NCBI GI #: 48145673
• NCBI GeneID: 3187
• UniProt Accession #: P31943; Q6IBM4; B3KW86; D3DWQ2
• Molecular Weight: 49,229 Da
• NCBI Official Full Name: HNRPH1
• NCBI Official Synonym Full Names: heterogeneous nuclear ribonucleoprotein H1 (H)
• NCBI Official Symbol: HNRNPH1
• NCBI Official Synonym Symbols: HNRPH; HNRPH1; hnRNPH
• NCBI Protein Information: heterogeneous nuclear ribonucleoprotein H
• UniProt Protein Name: Heterogeneous nuclear ribonucleoprotein H
• UniProt Gene Name: HNRNPH1
• UniProt Synonym Gene Names: HNRPH; HNRPH1; hnRNP H
• UniProt Entry Name: HNRH1_HUMAN

NCBI Description

This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described [provided by RefSeq, Mar 2012]

Uniprot Description

hnRNP H1: This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG).

Protein type: RNA-binding; RNA splicing; Spliceosome

Chromosomal Location of Human Ortholog: 5q35.3

Cellular Component: cytoplasm; membrane; nucleoplasm; nucleus

Molecular Function: nucleotide binding; poly(U) binding; protein binding; RNA binding

Biological Process: fibroblast growth factor receptor signaling pathway; gene expression; nuclear mRNA splicing, via spliceosome; regulation of RNA splicing; RNA processing