Western Blot (WB)
(Western blot analysis of hnRNP Q expression in HT1080 (A); HeLa (B); HuvEc (C) whole cell lysates.)
Rabbit hnRNPQ Polyclonal Antibody | anti-hnRNPQ antibody
hnRNPQ Antibody
IF: 1:100-1:500
ICC: 1:100-1:500
IP: 1:10-1:100
Western Blot (WB)
(Western blot analysis of hnRNP Q expression in HT1080 (A); HeLa (B); HuvEc (C) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of hnRNP Q expression in HT1080 (A); HeLa (B); HuvEc (C) whole cell lysates.)
NCBI and Uniprot Product Information
Uniprot Description
NSAP1: a heterogeneous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. A component of the spliceosome. Five alternatively spliced isoforms have been described. Isoform 1, 2 and 3 are associated with pre-mRNA, splicing intermediates and mature mRNA protein complexes. Isoform 1 binds to apoB mRNA AU-rich sequences. Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to ACF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. Isoform 3 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins.
Protein type: RNA-binding; Motility/polarity/chemotaxis; RNA splicing; Spliceosome
Chromosomal Location of Human Ortholog: 6q14-q15
Cellular Component: nucleoplasm; membrane; endoplasmic reticulum; nucleus; ribonucleoprotein complex
Molecular Function: protein binding; RNA binding; nucleotide binding; poly(A) binding
Biological Process: nuclear mRNA splicing, via spliceosome; osteoblast differentiation; RNA processing; viral reproduction; negative regulation of translation; RNA splicing
Similar Products
Product Notes
The hnRNPQ syncrip (Catalog #AAA5315427) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's hnRNPQ can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP). WB: 1:500-1:1000 IF: 1:100-1:500 ICC: 1:100-1:500 IP: 1:10-1:100. Researchers should empirically determine the suitability of the hnRNPQ syncrip for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "hnRNPQ, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
