Rabbit anti-Human HMGN1 Polyclonal Antibody | anti-hmgn1 antibody

HMGN1, NT (HMGN1, HMG14, Non-histone chromosomal protein HMG-14, High mobility group nucleosome-binding domain-containing protein 1)

Cat. Num. AAA647077

• Gene Names: hmgn1; hmg14
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: HMGN1; Polyclonal Antibody; NT (HMGN1; HMG14; Non-histone chromosomal protein HMG-14; High mobility group nucleosome-binding domain-containing protein 1); Anti -HMGN1; anti-hmgn1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-hmgn1 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in Western Blot, Immunohistochemistry, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500; Immunohistochemistry: 1:10-50
• Immunogen: HMGN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HMGN1.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(HMGN1 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the HMGN1 antibody detected the HMGN1 protein (arrow).)

Western Blot (WB)

(Western blot analysis of HMGN1 (arrow) using rabbit polyclonal HMGN1 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the HMGN1 gene.)

Immunohistochemistry (IHC)

(HMGN1 Antibody (N-term) (AP14219a)immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HMGN1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-hmgn1 antibody

Chromosomal protein HMG14 and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.

Product Categories/Family for anti-hmgn1 antibody

Antibodies; Abs to Histones

NCBI and Uniprot Product Information

• NCBI GI #: 89886086
• NCBI GeneID: 394660
• NCBI Accession #: NP_989063.2
• NCBI GenBank Nucleotide #: NM_203732.2
• NCBI Official Full Name: high mobility group nucleosome binding domain 1
• NCBI Official Synonym Full Names: high mobility group nucleosome binding domain 1
• NCBI Official Symbol: hmgn1
• NCBI Official Synonym Symbols: hmg14
• NCBI Protein Information: high mobility group nucleosome binding domain 1; high-mobility group nucleosome binding domain 1
• Protein Family: Non-histone chromosomal protein