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Western Blot (WB) (Western blot analysis of lysates from mouse brain tissue, using HMG-I/HMG-Y antibody.)

Rabbit HMG-I/HMG-Y Polyclonal Antibody | anti-HMG-I/HMG-Y antibody

HMG-I/HMG-Y Antibody

Gene Names
HMGA1; HMG-R; HMGIY; HMGA1A
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Synonyms
HMG-I/HMG-Y; Polyclonal Antibody; HMG-I/HMG-Y Antibody; high mobility group AT-hook 1; High mobility group AT-hook protein 1; High mobility group protein A1; high mobility group protein HMG-I/HMG-Y; High mobility group protein-R; HMG-I(Y); HMG1; HMG3; HMGA1; HMGB1; HMGIY; anti-HMG-I/HMG-Y antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
HMG-I/HMG-Y antibody detects endogenous levels of HMG-I/HMG-Y.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
179
Applicable Applications for anti-HMG-I/HMG-Y antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:10000
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human HMG-I/HMG-Y.
Immunogen Range
45-94
Preparation and Storage
Stable at -20 degree C for at least 1 year.

Western Blot (WB)

(Western blot analysis of lysates from mouse brain tissue, using HMG-I/HMG-Y antibody.)

Western Blot (WB) (Western blot analysis of lysates from mouse brain tissue, using HMG-I/HMG-Y antibody.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
11 kDa
NCBI Official Full Name
high mobility group protein HMG-I/HMG-Y isoform b
NCBI Official Synonym Full Names
high mobility group AT-hook 1
NCBI Official Symbol
HMGA1
NCBI Official Synonym Symbols
HMG-R; HMGIY; HMGA1A
NCBI Protein Information
high mobility group protein HMG-I/HMG-Y
UniProt Protein Name
High mobility group protein HMG-I/HMG-Y
UniProt Gene Name
HMGA1
UniProt Synonym Gene Names
HMGIY; HMG-I(Y); High mobility group protein A1

NCBI Description

This gene encodes a chromatin-associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT-rich regions in double-stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes. [provided by RefSeq, Jan 2016]

Uniprot Description

HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.

Research Articles on HMG-I/HMG-Y

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Product Notes

The HMG-I/HMG-Y hmga1 (Catalog #AAA9508875) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HMG-I/HMG-Y Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HMG-I/HMG-Y can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:10000. Researchers should empirically determine the suitability of the HMG-I/HMG-Y hmga1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HMG-I/HMG-Y, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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