Western Blot (WB)
(HM13 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the HM13 antibody detected the HM13 protein (arrow).)
Rabbit anti-Human HM13 Polyclonal Antibody | anti-HM13 antibody
HM13, CT (HM13, H13, IMP1, PSL3, SPP, Minor histocompatibility antigen H13, Intramembrane protease 1, Presenilin-like protein 3, Signal peptide peptidase) (FITC)
Gene Names
HM13; H13; SPP; IMP1; PSL3; IMPAS; SPPL1; PSENL3; IMPAS-1; MSTP086; dJ324O17.1
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
HM13; Polyclonal Antibody; CT (HM13; H13; IMP1; PSL3; SPP; Minor histocompatibility antigen H13; Intramembrane protease 1; Presenilin-like protein 3; Signal peptide peptidase) (FITC); Signal peptide peptidase; anti-HM13 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Applicable Applications for anti-HM13 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
HM13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-354 amino acids from the C-terminal region of human HM13.
Conjugate
FITC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(HM13 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the HM13 antibody detected the HM13 protein (arrow).)
Western Blot (WB)
(HM13 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the HM13 antibody detected the HM13 protein (arrow).)
Related Product Information for anti-HM13 antibody
The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene.
Product Categories/Family for anti-HM13 antibody
References
Sato, T., et al. Biochemistry 45(28):8649-8656(2006). Loureiro, J., et al. Nature 441(7095):894-897(2006). Urny, J., et al. Biochim. Biophys. Acta 1759 (3-4), 159-165 (2006): Friedmann, E., et al. J. Biol. Chem. 279(49):50790-50798(2004). Soares, M.R., et al. FEBS Lett. 560 (1-3), 134-140 (2004).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,488 Da
NCBI Official Full Name
minor histocompatibility antigen H13 isoform 1
NCBI Official Synonym Full Names
histocompatibility (minor) 13
NCBI Official Symbol
HM13
NCBI Official Synonym Symbols
H13; SPP; IMP1; PSL3; IMPAS; SPPL1; PSENL3; IMPAS-1; MSTP086; dJ324O17.1
NCBI Protein Information
minor histocompatibility antigen H13; IMP-1; hIMP1; intramembrane protease 1; presenilin-like protein 3; signal peptide peptidase beta; signal peptide peptidase like 1; minor histocompatibility antigen 13
UniProt Protein Name
Minor histocompatibility antigen H13
Protein Family
UniProt Gene Name
HM13
UniProt Synonym Gene Names
H13; IMP1; PSL3; SPP; MSTP086; IMP-1; IMPAS-1; hIMP1
UniProt Entry Name
HM13_HUMAN
Similar Products
Product Notes
The HM13 hm13 (Catalog #AAA6307179) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HM13, CT (HM13, H13, IMP1, PSL3, SPP, Minor histocompatibility antigen H13, Intramembrane protease 1, Presenilin-like protein 3, Signal peptide peptidase) (FITC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HM13 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the HM13 hm13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HM13, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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