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Goat HIVEP2/MIBP1 Polyclonal Antibody | anti-HIVEP2 antibody

Goat anti-HIVEP2/MIBP1 Antibody

Gene Names
HIVEP2; SHN2; ZAS2; MBP-2; MIBP1; ZNF40B; HIV-EP2
Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Applications
ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
HIVEP2/MIBP1; Polyclonal Antibody; Goat anti-HIVEP2/MIBP1 Antibody; HIVEP2; human immunodeficiency virus type I enhancer binding protein 2; HIV-EP2; MBP-2; MIBP1; SHN2; ZAS2; ZNF40B; MHC binding protein-2; OTTHUMP00000017321; OTTHUMP00000017322; OTTHUMP00000040180; Schnurri-2; c-myc intron binding protein 1; c-myc intron-; HIVEP2 antibody; human immunodeficiency virus type I enhancer binding protein 2 antibody; HIV-EP2 antibody; MBP-2 antibody; MIBP1 antibody; SHN2 antibody; ZAS2 antibody; ZNF40B antibody; MHC binding protein-2 antibody; OTTHUMP00000017321 antibody; OTTHUMP00000017322 antibody; OTTHUMP00000040180 antibody; Schnurri-2 antibody; c-myc intron binding protein 1 antibody; c-myc intron-binding protein 1 antibody; human immunodeficiency virus type I enhancer-binding protein 2 antibody; anti-HIVEP2 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
TEESKDPSSEKSQ
Sequence Length
2446
Applicable Applications for anti-HIVEP2 antibody
Peptide ELISA (EIA)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 1000.
Western Blot: Preliminary experiments in Human Lymph Node and Human Spleen lysates and in lysates of cell line MOLT4 gave no specific signal but low background (at antibody concentration up to 2ug/ml).
Immunogen
Peptide with sequence C-TEESKDPSSEKSQ, from the C Terminus of the protein sequence according to NP_006725.3.
Epitope
C Terminus
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
269,053 Da
NCBI Official Full Name
transcription factor HIVEP2
NCBI Official Synonym Full Names
human immunodeficiency virus type I enhancer binding protein 2
NCBI Official Symbol
HIVEP2
NCBI Official Synonym Symbols
SHN2; ZAS2; MBP-2; MIBP1; ZNF40B; HIV-EP2
NCBI Protein Information
transcription factor HIVEP2
UniProt Protein Name
Transcription factor HIVEP2
UniProt Gene Name
HIVEP2
UniProt Synonym Gene Names
HIV-EP2; MBP-2
UniProt Entry Name
ZEP2_HUMAN

NCBI Description

This gene encodes a member of a family of closely related, large, zinc finger-containing transcription factors. The encoded protein regulates transcription by binding to regulatory regions of various cellular and viral genes that maybe involved in growth, development and metastasis. The protein contains the ZAS domain comprised of two widely separated regions of zinc finger motifs, a stretch of highly acidic amino acids and a serine/threonine-rich sequence. [provided by RefSeq, Nov 2012]

Uniprot Description

HIVEP2: This protein specifically binds to the DNA sequence 5'- GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, somatostatin receptor II, and interferon- beta genes. It may act in T-cell activation.

Protein type: C2H2-type zinc finger protein; DNA-binding

Chromosomal Location of Human Ortholog: 6q23-q24

Cellular Component: nucleoplasm; nucleus

Molecular Function: DNA binding; metal ion binding; sequence-specific DNA binding; transcription factor activity

Biological Process: multicellular organismal development; regulation of transcription, DNA-dependent; signal transduction; transcription from RNA polymerase II promoter

Research Articles on HIVEP2

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Product Notes

The HIVEP2 hivep2 (Catalog #AAA421691) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-HIVEP2/MIBP1 Antibody reacts with Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow and may cross-react with other species as described in the data sheet. AAA Biotech's HIVEP2/MIBP1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 1000. Western Blot: Preliminary experiments in Human Lymph Node and Human Spleen lysates and in lysates of cell line MOLT4 gave no specific signal but low background (at antibody concentration up to 2ug/ml). Researchers should empirically determine the suitability of the HIVEP2 hivep2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: TEESKDPSSE KSQ. It is sometimes possible for the material contained within the vial of "HIVEP2/MIBP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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