Rabbit anti-HIV-1 M:B_MN HIV1 gp120 Polyclonal Antibody | anti-HIV1 antibody
HIV1 gp120 Antibody FITC Conjugated
Reactivity
HIV-1 M:B_MN
Applications
Immunofluorescence
Purity
Purified by Protein A
Synonyms
HIV1 gp120; Polyclonal Antibody; HIV1 gp120 Antibody FITC Conjugated; HIV-1 ENV gp120; HIV1gp120; HIV-1 gp120; Envelope surface glycoprotein gp120; Glycoprotein 120; gp120; gp120 glycoprotein; Human Immunodeficiency Virus 1; SU; Surface protein; ENV_HV1MN; Envelope glycoprotein gp160; Env polyprotein; Surface protein gp120; SU HIV1 gp120; anti-HIV1 antibody
Host
Rabbit
Reactivity
HIV-1 M:B_MN
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A
Form/Format
10mM Tris Buffered Saline containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Concentration
1mgml (varies by lot)
Applicable Applications for anti-HIV1 antibody
Immunofluorescence (IF)
Application Notes
IF: 1:50-200
Conjugation
FITC
Excitation Emission
494nm 518nm
Immunogen
KLH conjugated synthetic peptide aa 290-340 857 derived from HIV1 Surface protein gp120
Preparation and Storage
Store at 4 degree C for 12 months.
Related Product Information for anti-HIV1 antibody
The attachment of enveloped viruses to cells and the fusion of viral and cellular membranes are critical early events in the HIV viral infection. This process is mediated by envelope glycoproteins (gp) on the surface of the virus. The human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein, gp160, is proteolytically cleaved into gp120 and gp41, which remain noncovalently associated with one another. gp120 is one of the proteins that forms the envelope of HIV. gp120 projects from the surface of HIV and binds to the CD4 molecule on helper T cells. gp120 has been a logical experimental HIV vaccine because the outer envelope is the first part of the virus that encounters antibody. gp41 is embedded in the outer envelope of HIV that anchors gp120. gp41 also plays a key role in HIV's infection of CD4+ T cells by facilitating the fusion of the viral and cell membranes. The nomenclature of the gp proteins describes their respective molecular masses (e.g., gp160, gp120, gp41).
Product Categories/Family for anti-HIV1 antibody
NCBI and Uniprot Product Information
Uniprot Description
Envelope glycoprotein gp160: Oligomerizes in the host endoplasmic reticulum into predominantly trimers. In a second time, gp160 transits in the host Golgi, where glycosylation is completed. The precursor is then proteolytically cleaved in the trans-Golgi and thereby activated by cellular furin or furin-like proteases to produce gp120 and gp41.
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Product Notes
The HIV1 env (Catalog #AAA9459829) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HIV1 gp120 Antibody FITC Conjugated reacts with HIV-1 M:B_MN and may cross-react with other species as described in the data sheet. AAA Biotech's HIV1 gp120 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF). IF: 1:50-200. Researchers should empirically determine the suitability of the HIV1 env for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HIV1 gp120, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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