Western Blot (WB)
(Western blot analysis 1 ng of recombinant gp120 with gp120 antibody at 1 μg/mL.)
Rabbit anti-HIV-1 gp120 Polyclonal Antibody | anti-gp120 antibody
gp120 Antibody
Reactivity
HIV-1
Applications
ELISA, Western Blot
Purity
Affinity chromatography purified via peptide column.
Synonyms
gp120; Polyclonal Antibody; gp120 Antibody; Envelope glycoprotein gp160; env; anti-gp120 antibody
Host
Rabbit
Reactivity
HIV-1
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
847
Applicable Applications for anti-gp120 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
Western blot at 1 - 2 mug/mL.
Conjugate
Unconjugated
Immunogen
gp120 antibody was raised against a peptide corresponding to 15 amino acids near the center of HIV-1 gp120.
Buffer
gp120 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
Store at 4 degree C for three months and -20 degree C, stable for up to one year.
As with all antibodies care should be taken to avoid repeated freeze thaw cycles.
Antibodies should not be exposed to prolonged high temperatures.
As with all antibodies care should be taken to avoid repeated freeze thaw cycles.
Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis 1 ng of recombinant gp120 with gp120 antibody at 1 μg/mL.)
Western Blot (WB)
(Western blot analysis 1 ng of recombinant gp120 with gp120 antibody at 1 μg/mL.)
Related Product Information for anti-gp120 antibody
Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
Product Categories/Family for anti-gp120 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
Predicted: 120 kDa
Observed: 120 kDa
Observed: 120 kDa
NCBI Official Full Name
envelope glycoprotein
NCBI Official Symbol
env
NCBI Protein Information
gp160; envelope glycoprotein
UniProt Protein Name
Envelope glycoprotein gp160
UniProt Gene Name
env
UniProt Synonym Gene Names
SU; gp120; TM; gp41
Uniprot Description
gp160: The gp120-gp41 heterodimer allows rapid transcytosis of the virus through CD4 negative cells such as simple epithelial monolayers of the intestinal, rectal and endocervical epithelial barriers. Both gp120 and gp41 specifically recognize glycosphingolipids galactosyl-ceramide (GalCer) or 3' sulfo-galactosyl-ceramide (GalS) present in the lipid rafts structures of epithelial cells. Binding to these alternative receptors allows the rapid transcytosis of the virus through the epithelial cells. This transcytotic vesicle-mediated transport of virions from the apical side to the basolateral side of the epithelial cells does not involve infection of the cells themselves
Protein type: Apoptosis; Membrane protein, integral
Research Articles on gp120
Similar Products
Product Notes
The gp120 env (Catalog #AAA154466) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The gp120 Antibody reacts with HIV-1 and may cross-react with other species as described in the data sheet. AAA Biotech's gp120 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Western blot at 1 - 2 mug/mL. Researchers should empirically determine the suitability of the gp120 env for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "gp120, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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