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Western Blot (WB) (SH-SY5Y cells were subjected to SDS PAGE followed by western blot with MBS767916 (CHRNB4 antibody) at dilution of 1:500)

Rabbit anti-Human, Mouse CHRNB4 Polyclonal Antibody | anti-CHRNB4 antibody

CHRNB4 Rabbit Polyclonal

Reactivity
Human, Mouse
Applications
ELISA, Western Blot
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
CHRNB4; Polyclonal Antibody; CHRNB4 Rabbit Polyclonal; anti-CHRNB4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
198
Applicable Applications for anti-CHRNB4 antibody
ELISA (EIA), Western Blot (WB)
Immunogen
Cholinergic receptor, nicotinic, beta 4
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Western Blot (WB)

(SH-SY5Y cells were subjected to SDS PAGE followed by western blot with MBS767916 (CHRNB4 antibody) at dilution of 1:500)

Western Blot (WB) (SH-SY5Y cells were subjected to SDS PAGE followed by western blot with MBS767916 (CHRNB4 antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
25,862 Da
NCBI Official Full Name
CHRNB4 protein, partial
NCBI Official Synonym Full Names
cholinergic receptor nicotinic beta 4 subunit
NCBI Official Symbol
CHRNB4
NCBI Protein Information
neuronal acetylcholine receptor subunit beta-4
UniProt Protein Name
Neuronal acetylcholine receptor subunit beta-4
UniProt Gene Name
CHRNB4
UniProt Entry Name
ACHB4_HUMAN

Uniprot Description

nAChRB4: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Beta- 4/CHRNB4 sub-subfamily.

Protein type: Membrane protein, integral; Channel, ligand-gated; Channel, cation; Membrane protein, multi-pass; Receptor, misc.

Chromosomal Location of Human Ortholog: 15q24

Cellular Component: cell junction; integral to membrane; integral to plasma membrane; neuron projection; nicotinic acetylcholine-gated receptor-channel complex; plasma membrane; postsynaptic membrane

Molecular Function: acetylcholine binding; acetylcholine receptor activity; drug binding; ligand-gated ion channel activity; nicotinic acetylcholine-activated cation-selective channel activity; protein heterodimerization activity

Biological Process: behavioral response to nicotine; ion transport; locomotory behavior; positive regulation of transmission of nerve impulse; protein heterooligomerization; regulation of action potential; regulation of neurotransmitter secretion; regulation of smooth muscle contraction; response to nicotine; signal transduction; smooth muscle contraction; synaptic transmission involved in micturition; synaptic transmission, cholinergic

Research Articles on CHRNB4

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Product Notes

The CHRNB4 chrnb4 (Catalog #AAA767916) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CHRNB4 Rabbit Polyclonal reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CHRNB4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the CHRNB4 chrnb4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CHRNB4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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