Western Blot (WB)
(HEY2 Antibody (N-term) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the HEY2 antibody detected HEY2 protein (arrow).)
Rabbit anti-Human, Mouse HEY2 Polyclonal Antibody | anti-HEY2 antibody
HEY2, NT (HEY2, BHLHB32, CHF1, GRL, HERP, HERP1, HRT2, Hairy/enhancer-of-split related with YRPW motif protein 2, Cardiovascular helix-loop-helix factor 1, Class B basic helix-loop-helix protein 32, HES-related repressor protein 2, Hairy and enhancer of s
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Western Blot (WB)
(HEY2 Antibody (N-term) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the HEY2 antibody detected HEY2 protein (arrow).)
Western Blot (WB)
(HEY2 Antibody (N-term) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the HEY2 antibody detected HEY2 protein (arrow).)
Immunohistochemistry (IHC)
(HEY2 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.)
Immunohistochemistry (IHC)
(HEY2 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
Function: Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6. Ref.3 Ref.4 Ref.10 Ref.11
Subunit structure: May self-associate
By similarity. Interacts with GATA4, HES1 and HEYL
By similarity. Interacts with HDAC1, NCOR1 and SIN3A
By similarity. Interacts with ARNT and GATA6. Ref.3 Ref.11
Subcellular location: Nucleus
By similarity.
Sequence similarities: Belongs to the HEY family.Contains 1 bHLH (basic helix-loop-helix) domain.Contains 1 Orange domain.
Research Articles on HEY2
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Product Notes
The HEY2 hey2 (Catalog #AAA649356) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HEY2, NT (HEY2, BHLHB32, CHF1, GRL, HERP, HERP1, HRT2, Hairy/enhancer-of-split related with YRPW motif protein 2, Cardiovascular helix-loop-helix factor 1, Class B basic helix-loop-helix protein 32, HES-related repressor protein 2, Hairy and enhancer of s reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's HEY2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Western Blot, Immunohistochemistry, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100. Researchers should empirically determine the suitability of the HEY2 hey2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HEY2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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