Western Blot (WB)
(HECTD3 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the HECTD3 antibody detected the HECTD3 protein (arrow).)
Rabbit anti-Human HECTD3 Polyclonal Antibody | anti-HECTD3 antibody
HECTD3 Antibody (C-term)
Western Blot (WB)
(HECTD3 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the HECTD3 antibody detected the HECTD3 protein (arrow).)
Western Blot (WB)
(HECTD3 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the HECTD3 antibody detected the HECTD3 protein (arrow).)
Gevaert, K., et al. Nat. Biotechnol. 21(5):566-569(2003)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene transfers ubiquitin from an E2 ubiquitin-conjugating enzyme to targeted substrates, leading to the degradation of those substrates. The encoded protein has been shown to transfer ubiquitin to TRIOBP to facilitate cell cycle progression, and to STX8. [provided by RefSeq, Dec 2012]
Uniprot Description
HECTD3: E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus faciliting cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 6.3.2.-; Ubiquitin conjugating system; EC 6.3.2.19; Ubiquitin ligase; Ligase
Chromosomal Location of Human Ortholog: 1p34.1
Cellular Component: perinuclear region of cytoplasm; cytoplasm; nucleus
Molecular Function: protein binding; syntaxin binding; ubiquitin-protein ligase activity; ligase activity
Biological Process: proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination during ubiquitin-dependent protein catabolic process
Research Articles on HECTD3
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Product Notes
The HECTD3 hectd3 (Catalog #AAA9203706) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 740-769. The HECTD3 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HECTD3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the HECTD3 hectd3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HECTD3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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