Western Blot (WB)
(Western blot analysis of HDAC6 expression in Jurkat cell lysate.)
Rabbit HDAC6 Polyclonal Antibody | anti-HDAC6 antibody
HDAC6 Antibody
Gene Names
HDAC6; HD6; JM21; CPBHM; PPP1R90
Applications
Immunohistochemistry, Western Blot
Purity
Affinity Chromatography
Synonyms
HDAC6; Polyclonal Antibody; HDAC6 Antibody; Rabbit Polyclonal HDAC6 Antibody; Polyclonal HDAC6 antibody; anti-HDAC6 antibody; JM21 antibody; HDAC-6; HDAC-6 antibody; histone deacetylase 6 antibody; HD6 antibody; HDAC 6 antibody; HDAC 6
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Chromatography
Form/Format
Supplied in PBS buffer, pH 7.2, containing 30% Glycerol, 0.5% BSA, 0.01% Thimerosal
Concentration
200 ug/ml (varies by lot)
Sequence Length
1215
Applicable Applications for anti-HDAC6 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
IHC: 20 ug/ml
WB: 0.5-4 ug/ml
WB: 0.5-4 ug/ml
Immunogen
HDAC6 antibody was raised in Rabbit using synthetic peptide mapping to the N-terminus of mouse HDAC-6 as the immunogen.
Cross-Reactivity
Human, Mouse, Rat
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of HDAC6 expression in Jurkat cell lysate.)
Western Blot (WB)
(Western blot analysis of HDAC6 expression in Jurkat cell lysate.)
Related Product Information for anti-HDAC6 antibody
Human HDAC6 possesses two separate putative catalytic domains, both of which are fully functional and contribute independently to the overall activity of HDAC6. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. HDAC6 may participate in coordinating expression of a group of genes involved in the remoldeling of chromatin during cell differentiation.
Product Categories/Family for anti-HDAC6 antibody
NCBI and Uniprot Product Information
NCBI Description
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008]
Research Articles on HDAC6
Similar Products
Product Notes
The HDAC6 (Catalog #AAA5311392) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's HDAC6 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). IHC: 20 ug/ml WB: 0.5-4 ug/ml. Researchers should empirically determine the suitability of the HDAC6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HDAC6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
