Western Blot (WB)
(Western blot analysis of extracts from COS-7 cells, using HBP1 antibody.)
Rabbit HBP1 Polyclonal Antibody | anti-HBP1 antibody
HBP1 Antibody
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
HBP1; Polyclonal Antibody; HBP1 Antibody; HMG box-containing protein 1; High mobility group box transcription factor 1; anti-HBP1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total HBP1 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
524
Applicable Applications for anti-HBP1 antibody
Western Blot (WB)
Application Notes
Western blotting: 1:500~1:3000
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from Internal of human HBP1.
Target Name
HBP1
Preparation and Storage
Store at -20 degree C
Western Blot (WB)
(Western blot analysis of extracts from COS-7 cells, using HBP1 antibody.)
Western Blot (WB)
(Western blot analysis of extracts from COS-7 cells, using HBP1 antibody.)
Related Product Information for anti-HBP1 antibody
Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.Lemercier C., Mol. Cell. Biol. 20:6627-6637(2000).Hillier L.W., Nature 424:157-164(2003).Ota T., Nat. Genet. 36:40-45(2004).
Product Categories/Family for anti-HBP1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
57,699 Da
NCBI Official Full Name
HMG box-containing protein 1 isoform 1
NCBI Official Synonym Full Names
HMG-box transcription factor 1
NCBI Official Symbol
HBP1
NCBI Protein Information
HMG box-containing protein 1
UniProt Protein Name
HMG box-containing protein 1
Protein Family
UniProt Gene Name
HBP1
UniProt Entry Name
HBP1_HUMAN
Uniprot Description
HBP1: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 7q22.3
Cellular Component: nucleoplasm
Molecular Function: protein binding; DNA binding; RNA binding
Biological Process: Wnt receptor signaling pathway; regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of potassium ion transport; cell cycle arrest
Research Articles on HBP1
Similar Products
Product Notes
The HBP1 hbp1 (Catalog #AAA9403543) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HBP1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HBP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500~1:3000. Researchers should empirically determine the suitability of the HBP1 hbp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HBP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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