Western Blot (WB)
(Western blot analysis of anti-CSTF2 Antibody (N-term) in NCI-H460 cell line lysates (35ug/lane). CSTF2(arrow) was detected using the purified Pab.)
Rabbit Cleavage stimulation factor 2 (CSTF2) Polyclonal Antibody | anti-CSTF2 antibody
Cleavage stimulation factor 2 (CSTF2) Antibody (N-term)
Western Blot (WB)
(Western blot analysis of anti-CSTF2 Antibody (N-term) in NCI-H460 cell line lysates (35ug/lane). CSTF2(arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of anti-CSTF2 Antibody (N-term) in NCI-H460 cell line lysates (35ug/lane). CSTF2(arrow) was detected using the purified Pab.)
Martincic, K., et al., Proc. Natl. Acad. Sci. U.S.A. 95(19):11095-11100 (1998).
Takagaki, Y., et al., Cell 87(5):941-952 (1996).
Takagaki, Y., et al., Nature 372(6505):471-474 (1994).
Takagaki, Y., et al., Proc. Natl. Acad. Sci. U.S.A. 89(4):1403-1407 (1992).
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs. [provided by RefSeq, Jul 2008]
Uniprot Description
CSTF2: One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding; RNA splicing
Chromosomal Location of Human Ortholog: Xq22.1
Cellular Component: nucleoplasm; mRNA cleavage and polyadenylation specificity factor complex; nucleus
Molecular Function: protein binding; RNA binding; nucleotide binding
Biological Process: nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; RNA splicing; gene expression; mRNA polyadenylation; mRNA 3'-end processing; termination of RNA polymerase II transcription; mRNA cleavage
Research Articles on CSTF2
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Product Notes
The CSTF2 cstf2 (Catalog #AAA9212491) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 31-60. The Cleavage stimulation factor 2 (CSTF2) Antibody (N-term) reacts with Human (Predicted Reactivity: Bovine, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's Cleavage stimulation factor 2 (CSTF2) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the CSTF2 cstf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cleavage stimulation factor 2 (CSTF2), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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